Alterations in ubiquitin‐mediated degradation of NaV1.5 can cause arrhythmia
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DOI: 10.1111/apha.13459
Abstract: The voltage-gated sodium (NaV ) channel is required for cardiomyocyte function. In heart, its major, pore-forming, α-subunit is NaV 1.5, encoded by SCN5A, which maps to chromosome 3p21. The NaV channel plays a key role… read more here.
Keywords: cause arrhythmia; ubiquitin mediated; degradation nav1; alterations ubiquitin ... See more keywords