Caveolin-1 Regulates Atherogenesis by Attenuating LDL Transcytosis and Vascular Inflammation Independent of Endothelial Nitric Oxide Synthase Activation.
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DOI: 10.1161/circulationaha.118.038571
Abstract: BACKGROUND Atherosclerosis is driven by synergistic interactions between pathological biomechanical, inflammatory and lipid metabolic factors. Our previous studies demonstrated that absence of caveolin-1 (Cav1)/caveolae in hyperlipidemic mice strongly inhibits atherosclerosis, which was attributed to activation… read more here.
Keywords: caveolae; atherosclerosis; nitric oxide; cav1 caveolae ... See more keywords