Caveolin-1-mediated sphingolipid oncometabolism underlies a metabolic vulnerability of prostate cancer
Sign Up to like & getrecommendations! Published in 2020 at "Nature Communications"
DOI: 10.1038/s41467-020-17645-z
Abstract: Plasma and tumor caveolin-1 (Cav-1) are linked with disease progression in prostate cancer. Here we report that metabolomic profiling of longitudinal plasmas from a prospective cohort of 491 active surveillance (AS) participants indicates prominent elevations… read more here.
Keywords: cancer; caveolin mediated; metabolic vulnerability; prostate cancer ... See more keywords
Rab21 regulates caveolin‐1‐mediated endocytic trafficking to promote immature neurite pruning
Sign Up to like & getrecommendations! Published in 2023 at "EMBO Reports"
DOI: 10.15252/embr.202254701
Abstract: Transmembrane proteins are internalized by clathrin‐ and caveolin‐dependent endocytosis. Both pathways converge on early endosomes and are thought to share the small GTPase Rab5 as common regulator. In contrast to this notion, we show here… read more here.
Keywords: rab21; mediated endocytic; caveolin mediated; early endosomes ... See more keywords