Articles with "caveolin scaffolding" as a keyword



Photo by _k8_ from unsplash

The phospho–caveolin-1 scaffolding domain dampens force fluctuations in focal adhesions and promotes cancer cell migration

Sign Up to like & get
recommendations!
Published in 2017 at "Molecular Biology of the Cell"

DOI: 10.1091/mbc.e17-05-0278

Abstract: The caveolin scaffolding domain mediates the promigratory activity of Src-phosphorylated (on Y14) caveolin-1 and, specifically, regulation of vinculin tension in focal adhesions. This suggests that pY14Cav1 enhances cancer cell migration by promoting engagement of focal… read more here.

Keywords: caveolin scaffolding; scaffolding domain; caveolin; focal adhesions ... See more keywords
Photo by _k8_ from unsplash

Multiple subregions within the caveolin-1 scaffolding domain inhibit fibrosis, microvascular leakage, and monocyte migration

Sign Up to like & get
recommendations!
Published in 2022 at "PLoS ONE"

DOI: 10.1371/journal.pone.0264413

Abstract: The caveolin-1 scaffolding domain (CSD, amino acids 82–101 of caveolin-1) has been shown to suppress bleomycin-induced lung and skin fibrosis and angiotensin II (AngII)-induced myocardial fibrosis. To identify active subregions within CSD, we split its… read more here.

Keywords: caveolin scaffolding; microvascular leakage; subregions within; migration ... See more keywords