PHACE syndrome and cerebral cavernous malformations: association or simply microhemorrhages?
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DOI: 10.1007/s00381-017-3479-x
Abstract: Dear Editor: We read with great interest the article by Dr. Foster and colleagues titled BPHACE syndrome is associated with intracranial cavernous malformations^ [1]. The authors state that four of the six patients who met… read more here.
Keywords: phace; phace syndrome; association; cavernous malformations ... See more keywords
Intraosseous cavernous malformations of the skull: clinical characteristics and long-term surgical outcomes
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DOI: 10.1007/s10143-018-1042-1
Abstract: Intraosseous cavernous malformations (ICMs) of the skull are relatively rare, benign, and slow-growing tumors. Knowledge of these lesions is poor. The goals of this study were to describe the clinical manifestations, radiological features, and long-term… read more here.
Keywords: term; term surgical; surgical outcomes; long term ... See more keywords
Opto-chiasmatic apoplexy as a compartment syndrome? Anatomical and surgical considerations on two bleeding cavernous malformations
Sign Up to like & getrecommendations! Published in 2021 at "Clinical Neurology and Neurosurgery"
DOI: 10.1016/j.clineuro.2020.106439
Abstract: OBJECTIVE Opto-chiasmatic (OC) cavernous malformations are sporadic lesions that are often misdiagnosed clinically and radiologically. Presenting symptoms range from incidental findings to the more frequent and dramatic "chiasmal apoplexy." The present study aims to evaluate… read more here.
Keywords: compartment syndrome; opto chiasmatic; apoplexy compartment; cavernous malformations ... See more keywords
Relevance of CCM gene polymorphisms for clinical management of sporadic cerebral cavernous malformations
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DOI: 10.1016/j.jns.2017.06.043
Abstract: Cerebral cavernous malformations (CCMs) are clusters of capillaries in the brain that may cause focal deficits or seizures in affected patients. They occur in both sporadic and inherited autosomal dominant form. Germline mutations in CCM1,… read more here.
Keywords: ccm; cavernous malformations; cerebral cavernous; gene ... See more keywords
Intraoperative magnetic resonance imaging for cerebral cavernous malformations: When is it maybe worth it?
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DOI: 10.1016/j.jocn.2021.04.017
Abstract: OBJECTIVE Intraoperative magnetic resonance imaging (iMRI) can be useful for cerebral cavernous malformations (CCM) surgery. However, literature on this topic is scarce. We aim to investigate its clinical utility and propose criteria for the selection… read more here.
Keywords: resonance imaging; magnetic resonance; cavernous malformations; cerebral cavernous ... See more keywords
Pediatric Cerebral Cavernous Malformations.
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DOI: 10.1016/j.pediatrneurol.2020.11.004
Abstract: Cerebral cavernous malformations are the second most common vascular malformations in the central nervous system, and over one-third are found in children. Lesions may be solitary or multiple, be discovered incidentally, be sporadic, or be… read more here.
Keywords: cerebral cavernous; neurology; pediatric cerebral; cavernous malformations ... See more keywords
Hereditary multiple Cerebral Cavernous Malformations associated with Wilson’s Disease and Multiple Lypomatosis: case report
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DOI: 10.1016/j.wneu.2017.06.002
Abstract: We report on the patient with two Mendelian diseases – symptomatic multiple familial cerebral cavernous malformations (FCCMs) and Wilson’s disease. Genetic analysis revealed SNPs in genes CCM2 and CCM3, associated with cavernous malformations, and homozygote… read more here.
Keywords: report; cavernous malformations; hereditary multiple; cerebral cavernous ... See more keywords
The Differentially Expressed Genes of Human Sporadic Cerebral Cavernous Malformations.
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DOI: 10.1016/j.wneu.2018.02.002
Abstract: OBJECTIVES To understand the development of sporadic cerebral cavernous malformations (SCCM) comprehensively, we analyzed gene expression profiles in SCCMs by gene microarray. METHODS The total number of the specimens collected in our study was 14,… read more here.
Keywords: expressed genes; cavernous malformations; sporadic cerebral; cerebral cavernous ... See more keywords
Surgical Management and Functional Outcomes of Cavernous Malformations Involving the Medulla Oblongata.
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DOI: 10.1016/j.wneu.2018.07.229
Abstract: OBJECTIVE The aim of this study was to evaluate the clinical features, surgical complications, and functional outcomes of the surgical treatment of patients with cavernous malformations (CMs) involving the medulla oblongata. METHODS The charts of… read more here.
Keywords: medulla; medulla oblongata; functional outcomes; surgical management ... See more keywords
Symptomatic Hemorrhage From Cerebral Cavernous Malformations: Evidence from a Cohort Study.
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DOI: 10.1016/j.wneu.2019.12.035
Abstract: OBJECTIVES Patients with a cerebral cavernous malformation (CCM) can suffer from intracranial hemorrhages ranging from insignificant and chronic microbleeds to life-threatening hemorrhage. Current management decisions and patient counseling are based on a heterogeneous body of… read more here.
Keywords: symptomatic hemorrhage; evidence; hemorrhage; cohort ... See more keywords
Natural Course, Clinical Profile, and Treatment Strategies for Cerebral Cavernous Malformations.
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DOI: 10.1016/j.wneu.2021.08.134
Abstract: A large body of evidence has suggested that the natural biology for symptomatic cerebral cavernous malformations (CCMs) is dynamic. These lesions exhibit a temporal clustering epiphenomenon and usually manifest with multispectral clinical patterns, the most… read more here.
Keywords: clinical profile; cavernous malformations; treatment; cerebral cavernous ... See more keywords