Articles with "caz" as a keyword



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Cellulose-Acetate Coating by Integrating Ester Group with Zinc Salt for Dendrite-Free Zn Metal Anodes.

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Published in 2022 at "Small"

DOI: 10.1002/smll.202203327

Abstract: Zinc (Zn) metal is considered a potential anode owing to its high theoretical capacity, safety, and low cost. However, the dendrites and corresponding side reactions in aqueous electrolytes hinder their further development in environmentally-friendly energy… read more here.

Keywords: cellulose acetate; caz; ester group; zinc ... See more keywords
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FUS causes synaptic hyperexcitability in Drosophila dendritic arborization neurons

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Published in 2018 at "Brain Research"

DOI: 10.1016/j.brainres.2018.03.037

Abstract: Mutations in the nuclear localization signal of the RNA binding protein FUS cause both Frontotemporal Dementia (FTD) and Amyotrophic Lateral Sclerosis (ALS). These mutations result in a loss of FUS from the nucleus and the… read more here.

Keywords: drosophila; hyperexcitability; caz; fus ... See more keywords
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MIC Profiling of Ceftazidime-Avibactam against two Carbapenemase producing Klebsiella pneumoniae Isolates.

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Published in 2020 at "Journal of global antimicrobial resistance"

DOI: 10.1016/j.jgar.2020.10.014

Abstract: OBJECTIVE To correlate results of a modified susceptibility testing method to outcomes of ceftazidime-avibactam (CAZ/AVI) therapy. METHODS Two bloodstreamK. pneumoniae isolates (CAZ/AVI susceptible) from an abdominal source were recovered from 2 unrelated patients. Both patients… read more here.

Keywords: ceftazidime avibactam; caz avi; mic profiling; caz ... See more keywords
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Single β-lactams versus combinations as empiric therapy for infections with Pseudomonas aeruginosa: assessing the in vitro susceptibility

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Published in 2019 at "Infectious Diseases"

DOI: 10.1080/23744235.2019.1673900

Abstract: Abstract Background: While the value of combination versus monotherapy of infections with Pseudomonas aeruginosa infection is a subject of debate, increasing antimicrobial resistance of this pathogen makes it difficult to select appropriate empiric regimens. We… read more here.

Keywords: infections pseudomonas; pseudomonas aeruginosa; susceptibility; caz ... See more keywords

1313. MIC Profiling of Ceftazidime-Avibactam (CAZ/AVI) Against Two Carbapenemase producing Klebsiella pneumoniae Isolates

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Published in 2020 at "Open Forum Infectious Diseases"

DOI: 10.1093/ofid/ofaa439.1495

Abstract: Carbapenemases confer resistance against a broad range of beta-lactams with a prevalence of 40-60% among CRE (carbapenem-resistant Enterobacteriaceae). CAZ-AVI is commonly used to treat infections due to CPE (carbapenemase-producing Enterobacteriaceae), typically guided by susceptibility testing… read more here.

Keywords: carbapenemase producing; caz avi; mic profiling; caz ... See more keywords
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2409. Drug-Induced Liver Injury (DILI) in a National Cohort of Hospitalized Patients Treated With Aztreonam and Ceftazidime

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Published in 2018 at "Open Forum Infectious Diseases"

DOI: 10.1093/ofid/ofy210.2062

Abstract: Abstract Background DILI, although uncommon, can be a severe and even fatal complication of antibiotic use. The safety of novel regimens targeting MDR Gram-negative bacteria (GNB) is an important concern. Cephalosporins such as ceftazidime (CAZ)… read more here.

Keywords: patients treated; atm caz; caz; dili ... See more keywords
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2448. In vitro Activity of Ceftazidime–Avibactam Against Enterobacteriaceae Causing Intra-abdominal, Urinary Tract and Lower Respiratory Tract Infections Collected in Latin America as Part of the INFORM Global Surveillance Program, 2012–2016

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Published in 2018 at "Open Forum Infectious Diseases"

DOI: 10.1093/ofid/ofy210.2101

Abstract: Abstract Background The dissemination of multi-drug-resistant Enterobacteriaceae (MDR Eba) threatens the treatment of Gram-negative infections. Ceftazidime–avibactam (CAZ-AVI) is a novel antimicrobial with activity against Eba producing Class A, C and some Class D β-lactamases. This… read more here.

Keywords: caz avi; caz; vitro activity; tract ... See more keywords
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Pharmacokinetic-Pharmacodynamic Target Attainment Analyses To Determine Optimal Dosing of Ceftazidime-Avibactam for the Treatment of Acute Pulmonary Exacerbations in Patients with Cystic Fibrosis

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Published in 2017 at "Antimicrobial Agents and Chemotherapy"

DOI: 10.1128/aac.00988-17

Abstract: ABSTRACT Acute pulmonary exacerbations (APE) involving Pseudomonas aeruginosa are associated with increased morbidity and mortality in cystic fibrosis (CF) patients. Drug resistance is a significant challenge to treatment. Ceftazidime-avibactam (CZA) demonstrates excellent in vitro activity… read more here.

Keywords: caz; treatment; target; target attainment ... See more keywords
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Evaluation of the Vitek 2, Phoenix, and MicroScan for Antimicrobial Susceptibility Testing of Stenotrophomonas maltophilia

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Published in 2021 at "Journal of Clinical Microbiology"

DOI: 10.1128/jcm.00654-21

Abstract: Stenotrophomonas maltophilia causes high-mortality infections in immunocompromised hosts with limited therapeutic options. Many U.S. laboratories rely on commercial automated antimicrobial susceptibility tests (cASTs) and use CLSI breakpoints (BPs) for S. maltophilia. ABSTRACT Stenotrophomonas maltophilia causes… read more here.

Keywords: phoenix; caz; vitek; stenotrophomonas maltophilia ... See more keywords
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OXA-48-Mediated Ceftazidime-Avibactam Resistance Is Associated with Evolutionary Trade-Offs

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Published in 2019 at "mSphere"

DOI: 10.1128/msphere.00024-19

Abstract: The recent introduction of novel β-lactam/β-lactamase inhibitor combinations like ceftazidime-avibactam has increased our ability to treat infections caused by multidrug-resistant Gram-negative bacteria, including carbapenemase-producing Enterobacterales. However, the increasing number of cases of reported resistance to… read more here.

Keywords: ceftazidime avibactam; caz; resistance; effect ... See more keywords
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Suboptimal Concentrations of Ceftazidime/Avibactam (CAZ-AVI) May Select for CAZ-AVI Resistance in Extensively Drug-Resistant Pseudomonas aeruginosa: In Vivo and In Vitro Evidence

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Published in 2022 at "Antibiotics"

DOI: 10.3390/antibiotics11111456

Abstract: This study correlates in vivo findings in a patient with an extensively drug-resistant (XDR) P. aeruginosa infection who developed resistance to ceftazidime-avibactam (CAZ-AVI) with in vitro results of a 7-day hollow-fiber infection model (HFIM) testing… read more here.

Keywords: caz; caz avi; extensively drug; resistance ... See more keywords