CB1 Cannabinoid Receptors Mediate Cognitive Deficits and Structural Plasticity Changes During Nicotine Withdrawal
Sign Up to like & getrecommendations! Published in 2017 at "Biological Psychiatry"
DOI: 10.1016/j.biopsych.2016.07.007
Abstract: BACKGROUND Tobacco withdrawal is associated with deficits in cognitive function, including attention, working memory, and episodic memory. Understanding the neurobiological mechanisms involved in these effects is crucial because cognitive deficits during nicotine withdrawal may predict… read more here.
Keywords: cognitive deficits; cannabinoid receptors; cb1 cannabinoid; structural plasticity ... See more keywords
CB1 cannabinoid receptor agonist mouse VD-hemopressin(α) produced supraspinal analgesic activity in the preclinical models of pain
Sign Up to like & getrecommendations! Published in 2018 at "Brain Research"
DOI: 10.1016/j.brainres.2017.12.013
Abstract: Mouse VD-hemopressin(α) (VD-Hpα) is an undecapeptide that selectively activates CB1 cannabinoid receptor in in vitro functional tests, and exerts CB1-mediated central antinociception in the mouse tail-flick assay. The aim of the present study was to… read more here.
Keywords: agonist; cb1 cannabinoid; mouse hemopressin; receptor ... See more keywords
Differential Expression of CB1 Cannabinoid Receptor and Cannabinoid Receptor Interacting Protein 1a in Labor.
Sign Up to like & getrecommendations! Published in 2021 at "Cannabis and cannabinoid research"
DOI: 10.1089/can.2020.0107
Abstract: Background: The endocannabinoid system is present in multiple organ systems and is involved in smooth muscle regulation, immune function, neuroendocrine modulation, and metabolism of tissues. Limited data are available regarding the presence and role of… read more here.
Keywords: system; labor; cb1 cannabinoid; cannabinoid ... See more keywords
Evaluation of the profiles of CB1 cannabinoid receptor signalling bias using joint kinetic modelling
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DOI: 10.1111/bph.15066
Abstract: Biased agonism describes the ability of ligands to differentially regulate multiple signalling pathways when coupled to a single receptor. Signalling is affected by rapid agonist‐induced receptor internalisation. Hence, the conventional use of equilibrium models may… read more here.
Keywords: receptor signalling; evaluation profiles; profiles cb1; cb1 cannabinoid ... See more keywords
Regional redistribution of CB1 cannabinoid receptors in human foetal brains with Down's syndrome and their functional modifications in Ts65Dn+/+ mice
Sign Up to like & getrecommendations! Published in 2023 at "Neuropathology and Applied Neurobiology"
DOI: 10.1111/nan.12887
Abstract: The endocannabinoid system with its type 1 cannabinoid receptor (CB1R) expressed in postmitotic neuroblasts is a critical chemotropic guidance module with its actions cascading across neurogenic commitment, neuronal polarisation and synaptogenesis in vertebrates. Here, we… read more here.
Keywords: cannabinoid receptors; cannabinoid; cb1r; regional redistribution ... See more keywords
CB1 Cannabinoid Receptor Signaling and Biased Signaling
Sign Up to like & getrecommendations! Published in 2021 at "Molecules"
DOI: 10.3390/molecules26175413
Abstract: The CB1 cannabinoid receptor is a G-protein coupled receptor highly expressed throughout the central nervous system that is a promising target for the treatment of various disorders, including anxiety, pain, and neurodegeneration. Despite the wide… read more here.
Keywords: cannabinoid receptor; biased signaling; cb1 cannabinoid; cb1 ... See more keywords