Assessment of select synthetic cannabinoid receptor agonist bias and selectivity between the type 1 and type 2 cannabinoid receptor
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-90167-w
Abstract: The first synthetic cannabinoid receptor agonists (SCRAs) were designed as tool compounds to study the endocannabinoid system’s two predominant cannabinoid receptors, CB1R and CB2R. Unfortunately, novel SCRAs now represent the most rapidly proliferating novel psychoactive… read more here.
Keywords: synthetic cannabinoid; cannabinoid; cannabinoid receptor; type ... See more keywords
Interaction between Cannabinoid Type 1 and Type 2 Receptors in the Modulation of Subventricular Zone and Dentate Gyrus Neurogenesis
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DOI: 10.3389/fphar.2017.00516
Abstract: Neurogenesis in the adult mammalian brain occurs mainly in two neurogenic niches, the subventricular zone (SVZ) and the subgranular zone (SGZ) of the dentate gyrus (DG). Cannabinoid type 1 and 2 receptors (CB1R and CB2R)… read more here.
Keywords: zone; neurogenesis; cannabinoid; cb1r cb2r ... See more keywords
Role of Major Endocannabinoid-Binding Receptors during Mouse Oocyte Maturation
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DOI: 10.3390/ijms20122866
Abstract: Endocannabinoids are key-players of female fertility and potential biomarkers of reproductive dysfunctions. Here, we investigated localization and expression of cannabinoid receptor type-1 and -2 (CB1R and CB2R), G-protein coupled receptor 55 (GPR55), and transient receptor… read more here.
Keywords: cb1r; gpr55; cb2r gpr55; cb1r cb2r ... See more keywords