Articles with "cbl" as a keyword



Effectiveness of Combining SDL and CBL in Postgraduate Orthodontic Education: A Randomized Trial and Surveys.

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Published in 2025 at "Journal of dental education"

DOI: 10.1002/jdd.70003

Abstract: PURPOSE Self-directed learning (SDL) is now combined with traditional case-based learning (CBL). The purpose of this study was to investigate and compare the teaching outcomes and impacts on self-assessment of the SDL-CBL teaching method and… read more here.

Keywords: traditional cbl; sdl cbl; group; cbl ... See more keywords

Tissue distribution of oral vitamin B12 is influenced by B12 status and B12 form: an experimental study in rats

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Published in 2017 at "European Journal of Nutrition"

DOI: 10.1007/s00394-017-1424-0

Abstract: PurposeHydroxocobalamin (HOCbl) is the dominating Cbl form in food, whereas cyanocobalamin (CNCbl) is common in vitamin pills and oral supplements. This study compares single-dose absorption and distribution of oral HO[57Co]Cbl and CN[57Co]Cbl in Cbl-deficient and… read more here.

Keywords: distribution oral; cbl; 57co cbl; form ... See more keywords

Nanodelivery of Cerebrolysin and Rearing in Enriched Environment Induce Neuroprotective Effects in a Preclinical Rat Model of Parkinson’s Disease

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Published in 2017 at "Molecular Neurobiology"

DOI: 10.1007/s12035-017-0741-x

Abstract: Rearing in enriched environment (EE) improves the recuperation in animal models of Parkinson’s disease (PD). Administration of TiO2-nanowired cerebrolysin (CBL) could represent an additional strategy to protect or repair the nigrostriatal system. This study aims… read more here.

Keywords: cbl; enriched environment; rearing enriched; group ... See more keywords
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A novel, germline, deactivating CBL variant p.L493F alters domain orientation and is associated with multiple childhood cancers.

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Published in 2021 at "Cancer genetics"

DOI: 10.1016/j.cancergen.2021.01.008

Abstract: CBL is a mammalian gene encoding the protein CBL, which is an E3 ubiquitin-protein ligase involved in cell signaling and protein ubiquitination. Pathogenic variants in this gene have been implicated in a number of human… read more here.

Keywords: cbl; germline deactivating; deactivating cbl; cbl variant ... See more keywords

C-Cbl and Cbl-b expression in skull base chordomas is associated with tumor progression and poor prognosis.

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Published in 2018 at "Human pathology"

DOI: 10.1016/j.humpath.2017.12.019

Abstract: Chordomas are rare, locally aggressive malignancies that are often difficult to eradicate. Surgery and radiotherapy are the first-line treatments, but the probability of local recurrence is high. According to our previous research, c-Cbl and Cbl-b… read more here.

Keywords: base chordomas; cbl; skull base; cbl cbl ... See more keywords

Double fullerene cathode buffer layers afford highly efficient and stable inverted planar perovskite solar cells

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Published in 2020 at "Organic Electronics"

DOI: 10.1016/j.orgel.2020.105726

Abstract: Abstract Fullerene derivatives especially [6,6]-phenyl-C61-butyric acid methyl ester (PCBM) with strong electron-accepting abilities have been commonly implemented as indispensable cathode buffer layers (CBLs) of inverted (p-i-n) planar perovskite solar cells (iPSCs) to facilitate electron transport.… read more here.

Keywords: double fullerene; cbl; cathode; fullerene cbl ... See more keywords

Identification of ABC transporters acting in vitamin B12 metabolism in Caenorhabditis elegans.

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Published in 2017 at "Molecular genetics and metabolism"

DOI: 10.1016/j.ymgme.2017.11.002

Abstract: Vitamin B12 (cobalamin, Cbl) is a micronutrient essential to human health. Cbl is not utilized as is but must go through complex subcellular and metabolic processing to generate two cofactor forms: methyl-Cbl for methionine synthase,… read more here.

Keywords: abc transporters; vitamin b12; cbl;

"NO" Means Yes: Unlocking the Therapeutic Synergy of Nitric Oxide (NO) and Chlorambucil (Cbl) via Photoresponsive Sequential Delivery in a Triple-Negative Breast Cancer 3D Spheroidal Platform with Transcriptomic Insights.

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Published in 2025 at "Journal of medicinal chemistry"

DOI: 10.1021/acs.jmedchem.5c01995

Abstract: Nitric oxide (NO) is a multifunctional signaling molecule in oncology, influencing tumor progression, apoptosis, and immune responses. In contrast, chlorambucil (Cbl), a DNA-alkylating chemotherapeutic, induces cytotoxicity through DNA damage. Here, we report a photoresponsive nanoparticle… read more here.

Keywords: chlorambucil cbl; breast cancer; negative breast; cbl ... See more keywords

Rs4911154 of circ-ITCH aggravated tumor malignancy of thyroid nodules via the circ-ITCH/miR-22-3p/CBL axis

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Published in 2021 at "Scientific Reports"

DOI: 10.1038/s41598-021-97471-5

Abstract: Recent evidence revealed an inhibitory effect of circ-ITCH on the progression of papillary thyroid cancer via affecting the circ-ITCH/miR-22-3p/CBL axis. Rs4911154, an SNP located in circ-ITHC, was previously reported to be significantly associated with an… read more here.

Keywords: thyroid nodules; itch; cbl; mir ... See more keywords

MSC-derived exosomal circMYO9B accelerates diabetic wound healing by promoting angiogenesis through the hnRNPU/CBL/KDM1A/VEGFA axis

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Published in 2024 at "Communications Biology"

DOI: 10.1038/s42003-024-07367-z

Abstract: Diabetic foot ulcer (DFU) is a common but devastating complication of diabetes mellitus and might ultimately lead to amputation. Elucidating the regulatory mechanism of wound healing in DFU is quite important for developing DFU management… read more here.

Keywords: vegfa; cbl; wound healing; kdm1a ... See more keywords

DC and RF performance analysis of enhancement mode fin-shaped tri-gate AlGaN/GaN HEMT and MOSHEMT with ultra-thin barrier layer

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Published in 2024 at "Physica Scripta"

DOI: 10.1088/1402-4896/ad5235

Abstract: The DC and RF assessment of critical barrier-AlGaN/GaN nano channel tri-gate fin-shaped High Electron Mobility Transistor (FinHEMT) is investigated for Enhancement-mode (E-mode) operation. We propose and analyze critical barrier layer (CBL) and critical-strained barrier layer… read more here.

Keywords: layer; tri gate; cbl; algan gan ... See more keywords