Crosstalk between the CBM complex/NF-κB and MAPK/P27 signaling pathways of regulatory T cells contributes to the tumor microenvironment
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.911811
Abstract: Regulatory T cells (Tregs), which execute their immunosuppressive functions by multiple mechanisms, have been verified to contribute to the tumor microenvironment (TME). Numerous studies have shown that the activation of the CBM complex/NF-κB signaling pathway… read more here.
Keywords: regulatory cells; cbm complex; tumor microenvironment; p27 signaling ... See more keywords
CARD9 Forms an Alternative CBM Complex in Richter Syndrome
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DOI: 10.3390/cancers14030531
Abstract: Simple Summary The transformation process of chronic lymphocytic leukemia into an aggressive lymphoma, called Richter syndrome (RS), is incompletely understood, and therapeutic options are limited. Here, we report CARD9 to be expressed in a subset… read more here.
Keywords: richter; card9; cell; richter syndrome ... See more keywords