A nucleation barrier spring-loads the CBM signalosome for binary activation
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DOI: 10.1101/2022.01.28.477912
Abstract: Immune cells activate in a binary, switch-like fashion that involves proteins polymerizing into large complexes known as signalosomes. The switch-like nature of signalosome formation has been proposed to result from large energy barriers to polymer… read more here.
Keywords: bcl10; nucleation; barrier; cbm signalosome ... See more keywords