CBX3 promotes tumor proliferation by regulating G1/S phase via p21 downregulation and associates with poor prognosis in tongue squamous cell carcinoma.
Sign Up to like & getrecommendations! Published in 2018 at "Gene"
DOI: 10.1016/j.gene.2018.02.043
Abstract: Chromobox protein homolog 3 (CBX3), a core component of the heterochromatin proteins 1, is recently proved to be involved in human cancerogenesis and associated with the prognosis of patient. However, the role of CBX3 in… read more here.
Keywords: tongue squamous; cell carcinoma; squamous cell; proliferation ... See more keywords
A Ubiquitous Chromatin Opening Element and DNA Demethylation Facilitate Doxycycline-Controlled Expression during Differentiation and in Transgenic Mice
Sign Up to like & getrecommendations! Published in 2023 at "ACS Synthetic Biology"
DOI: 10.1021/acssynbio.2c00450
Abstract: Synthetic expression cassettes provide the ability to control transgene expression in experimental animal models through external triggers, enabling the study of gene function and the modulation of endogenous regulatory networks in vivo. The performance of… read more here.
Keywords: doxycycline controlled; doxycycline; cbx3; controlled expression ... See more keywords
CBX3 regulated by miR-139 promotes the development of HCC by regulating cell cycle progression.
Sign Up to like & getrecommendations! Published in 2022 at "Cell cycle"
DOI: 10.1080/15384101.2022.2068329
Abstract: Hepatocellular carcinoma (HCC), a major primary liver cancer, is one of the most lethal malignancies worldwide. Increasing evidence has demonstrated that chromobox protein homolog 3 (CBX3) functions as an oncogene in different cancers. However, its… read more here.
Keywords: cell cycle; mir 139; hcc; cbx3 ... See more keywords
CBX3 is a Prognostic Biomarker Correlated with ATR Activation and Immune Infiltration in Head and Neck Squamous Cell Carcinoma
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of General Medicine"
DOI: 10.2147/ijgm.s344390
Abstract: Background Chromobox protein homolog (CBX) family members play important roles in the progression and prognosis of many cancers. However, their functional role in head and neck squamous cell carcinoma (HNSCC) remains largely unknown. Methods In… read more here.
Keywords: head neck; immune infiltration; cbx3; expression ... See more keywords
Members of the Chromobox Family Have Prognostic Value in Hepatocellular Carcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2022.887925
Abstract: Liver cancer is the fifth most prevalent malignant tumor, while hepatocellular carcinoma represents the most prevalent subtype worldwide. Previous studies have associated the chromobox family, critical components of epigenetic regulatory complexes, with development of many… read more here.
Keywords: carcinoma patients; hepatocellular carcinoma; cbx3; chromobox family ... See more keywords
Analysis of Pan-Cancer Revealed the Immunological and Prognostic Potential of CBX3 in Human Tumors
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Medicine"
DOI: 10.3389/fmed.2022.869994
Abstract: Chromobox protein homolog 3 (CBX3) has been recognized as a member of the heterochromatin protein 1 family and participate in transcriptional activation or inhibition, cell differentiation and growth. Despite more and more evidence shows that… read more here.
Keywords: pan cancer; cbx3; analysis pan; cancer revealed ... See more keywords
CBX3 Regulated By YBX1 Promotes Smoking-induced Pancreatic Cancer Progression via Inhibiting SMURF2 Expression
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Biological Sciences"
DOI: 10.7150/ijbs.68995
Abstract: As a key reversible and heritable mechanism of transcriptional regulation, the epigenetic modification plays a crucial role in tumorigenesis. Of note, tobacco smoking induces epigenetic modifications to promote pancreatic cancer development. Chromobox protein homolog 3… read more here.
Keywords: pancreatic cancer; induced pancreatic; cbx3; cancer progression ... See more keywords