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   Articles with "cbx4" as a keyword



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RING finger gene 180 inhibits osteosarcoma progression through regulating chromobox homolog 4 ubiquitination

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recommendations! Published in 2023 at "Cell Cycle"

DOI: 10.1080/15384101.2023.2205201

Abstract: ABSTRACT Osteosarcoma (OS) is still the most common malignant bone tumor whose etiology remains largely unclear. Here, we aimed to investigate the role of a novel E3 ubiquitin ligase RING finger gene 180 (RNF180) in… read more here.

Keywords: cbx4; ring finger; finger gene; rnf180 ... See more keywords
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Role of CBX4 in the Colorectal Carcinoma Metastasis-Response.

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recommendations! Published in 2017 at "Cancer research"

DOI: 10.1158/0008-5472.can-17-0594

Abstract: In our article ([1][1]), we have reported that CBX4 may serve as a tumor suppressor in colorectal carcinoma by recruiting HDAC3 to the RUNX2 promoter to impede RUNX2 expression and that this novel function of… read more here.

Keywords: colorectal carcinoma; cbx4; role cbx4; cbx4 colorectal ... See more keywords
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CBX4 Regulates Long-Form Thymic Stromal Lymphopoietin-Mediated Airway Inflammation Through SUMOylation in HDM-Induced Asthma.

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recommendations! Published in 2022 at "American journal of respiratory cell and molecular biology"

DOI: 10.1165/rcmb.2021-0301oc

Abstract: Thymic stromal lymphopoietin (TSLP) presents in two distinct isoforms: short-form (sfTSLP) and long-form (lfTSLP). lfTSLP promotes inflammation while sfTSLP inhibits inflammation in allergic asthma. However, little is known about the regulation of lfTSLP and sfTSLP… read more here.

Keywords: inflammation; sumoylation; stromal lymphopoietin; cbx4 ... See more keywords
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CBX4 Provides an Alternate Mode of Colon Cancer Development via Potential Influences on Circadian Rhythm and Immune Infiltration

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recommendations! Published in 2021 at "Frontiers in Cell and Developmental Biology"

DOI: 10.3389/fcell.2021.669254

Abstract: The circadian machinery is critical for the normal physiological functions and cellular processes. Circadian rhythm disruption has been associated with immune suppression which leads to higher cancer risk, suggesting a putative tumor protective role of… read more here.

Keywords: cancer; cbx4; colon cancer; circadian rhythm ... See more keywords