Effect of CBX7 deficiency on the socket healing after tooth extractions
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Bone and Mineral Metabolism"
DOI: 10.1007/s00774-018-0958-4
Abstract: CBX7 is shown to down-regulate the expression of osteopontin (OPN) that is associated with osteoblast function. Here, we studied the role of CBX7 in the wound healing of tooth extraction socket in which osteoblast activity… read more here.
Keywords: cbx7 mice; socket; bone; cbx7 ... See more keywords
Polycomb protein family member CBX7 regulates intrinsic axon growth and regeneration
Sign Up to like & getrecommendations! Published in 2018 at "Cell Death and Differentiation"
DOI: 10.1038/s41418-018-0064-0
Abstract: Neurons in the central nervous system (CNS) lose their intrinsic ability and fail to regenerate, but the underlying mechanisms are largely unknown. Polycomb group (PcG) proteins, which include PRC1 and PRC2 complexes function as gene… read more here.
Keywords: growth regeneration; axon growth; polycomb; regeneration ... See more keywords
Mammalian CBX7 isoforms p36 and p22 exhibit differential responses to serum, varying functions for proliferation, and distinct subcellular localization
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-64908-2
Abstract: CBX7 is a polycomb group protein, and despite being implicated in many diseases, its role in cell proliferation has been controversial: some groups described its pro-proliferative properties, but others illustrated its inhibitory effects on cell… read more here.
Keywords: cbx7 isoforms; cell proliferation; mammalian cbx7; isoforms p36 ... See more keywords
Integrated analysis of lncRNA-associated ceRNA network identified potential regulatory interactions in osteosarcoma
Sign Up to like & getrecommendations! Published in 2020 at "Genetics and Molecular Biology"
DOI: 10.1590/1678-4685-gmb-2019-0090
Abstract: Abstract This study aimed to identify potential therapeutic targets in osteosarcoma (OS) through the network analysis of competing endogenous RNAs (ceRNAs). The differentially expressed miRNAs (DEMIs) and mRNAs (DEMs) were identified between OS cell lines… read more here.
Keywords: analysis; cerna network; cbx7; mir 34a ... See more keywords
CBX7 suppresses cell proliferation, migration, and invasion through the inhibition of PTEN/Akt signaling in pancreatic cancer
Sign Up to like & getrecommendations! Published in 2017 at "Oncotarget"
DOI: 10.18632/oncotarget.14037
Abstract: Chromobox protein homolog 7 (CBX7), one of the polycomb group (PcG) proteins, is a transcriptional repressor involved in the regulation of cell proliferation and senescence. In the present study, we showed that CBX7 negatively regulates… read more here.
Keywords: pten akt; pancreatic cancer; proliferation; cancer cells ... See more keywords
CBX Family Members in Two Major Subtypes of Renal Cell Carcinoma: A Comparative Bioinformatic Analysis
Sign Up to like & getrecommendations! Published in 2022 at "Diagnostics"
DOI: 10.3390/diagnostics12102452
Abstract: The biological function and clinical values of Chromobox (CBX) family proteins in renal cell carcinoma (RCC) are still poorly investigated. This study aimed to compare the expression profiles and clinical relevance of CBXs between the… read more here.
Keywords: cell; cell carcinoma; renal cell; cbx family ... See more keywords