Tg.rasH2 Mice and not CByB6F1 Mice Should Be Used for 28-Day Dose Range Finding Studies Prior to 26-Week Tg.rasH2 Carcinogenicity Studies
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DOI: 10.1177/1091581817707458
Abstract: Our recent retrospective analysis of data, collected from 29 Tg.rasH2 mouse carcinogenicity studies, determined how successful the strategy of choosing the high dose for the 26-week studies was based on the estimated maximum tolerated dose… read more here.
Keywords: rash2 mice; cbyb6f1 mice; week; carcinogenicity studies ... See more keywords