The CCAAT‐binding complex mediates azole susceptibility of Aspergillus fumigatus by suppressing SrbA expression and cleavage
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DOI: 10.1002/mbo3.1249
Abstract: In fungal pathogens, the transcription factor SrbA (a sterol regulatory element‐binding protein, SREBP) and CBC (CCAAT binding complex) have been reported to regulate azole resistance by competitively binding the TR34 region (34 mer) in the… read more here.
Keywords: expression cleavage; expression; cleavage; ccaat binding ... See more keywords
The CCAAT-Binding Complex Controls Respiratory Gene Expression and Iron Homeostasis in Candida Glabrata
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DOI: 10.1038/s41598-017-03750-5
Abstract: The CCAAT-binding complex (CBC) is a heterotrimeric transcription factor which is widely conserved in eukaryotes. In the model yeast S. cerevisiae, CBC positively controls the expression of respiratory pathway genes. This role involves interactions with… read more here.
Keywords: iron homeostasis; glabrata; expression; iron ... See more keywords
The Iron-Dependent Regulation of the Candida albicans Oxidative Stress Response by the CCAAT-Binding Factor
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DOI: 10.1371/journal.pone.0170649
Abstract: Candida albicans is the most frequently encountered fungal pathogen in humans, capable of causing mucocutaneous and systemic infections in immunocompromised individuals. C. albicans virulence is influenced by multiple factors. Importantly, iron acquisition and avoidance of… read more here.
Keywords: response; iron; factor; ccaat binding ... See more keywords