Articles with "ccaat enhancer" as a keyword



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Thrombopoietic effects of CCAAT/enhancer-binding protein β on the early-stage differentiation of megakaryocytes.

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Published in 2021 at "Archives of biochemistry and biophysics"

DOI: 10.1016/j.abb.2021.108846

Abstract: CCAAT/enhancer-binding protein β (C/EBPβ) is a transcription factor that is involved in adipocytic and monocytic differentiation. However, the physiological role of C/EBPβ in megakaryocytes (MKs) is not clear. In this study, we investigated the effects… read more here.

Keywords: ccaat enhancer; enhancer binding; differentiation; binding protein ... See more keywords
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Atorvastatin prevents Angiotensin II induced myocardial hypertrophy in vitro via CCAAT/enhancer-binding protein β.

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Published in 2017 at "Biochemical and biophysical research communications"

DOI: 10.1016/j.bbrc.2017.03.057

Abstract: Previous evidences suggested that atorvastatin not only reduced blood lipids but also reduced myocardial hypertrophy and remodeling. And it was reported that C/EBPβ (CCAAT/enhancer-binding protein β) played a pivotal role both in the physiologic and… read more here.

Keywords: ccaat enhancer; atorvastatin; hypertrophy; enhancer binding ... See more keywords
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CCAAT/Enhancer‐binding protein &bgr; promotes pathogenesis of EAE

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Published in 2017 at "Cytokine"

DOI: 10.1016/j.cyto.2017.01.005

Abstract: HIGHLIGHTSCebpb−/− mice are resistant to EAE.In vivo Th17 responses are impaired in absence of C/EBP&bgr;.Th17 differentiation is normal in APC‐free cultures.C/EBP&bgr; binds to the IL‐23R in myeloid and Th17 cells. ABSTRACT The CCAAT/Enhancer Binding Protein… read more here.

Keywords: ccaat enhancer; ebp bgr; bgr; eae ... See more keywords
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Vaspin is a novel target gene of hepatic CCAAT-enhancer-binding protein.

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Published in 2019 at "Gene"

DOI: 10.1016/j.gene.2019.144113

Abstract: Vaspin, initially identified in visceral adipose tissue, is an adipokine, and administration of recombinant vaspin leads to lowering of the endoplasmic reticulum stress which is elevated in obesity or enhancement of insulin sensitivity. CCAAT/enhancer binding… read more here.

Keywords: ccaat enhancer; enhancer binding; binding protein; vaspin novel ... See more keywords
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CCAAT/Enhancer binding protein β silencing mitigates glial activation and neurodegeneration in a rat model of Parkinson’s disease

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Published in 2017 at "Scientific Reports"

DOI: 10.1038/s41598-017-13269-4

Abstract: The CCAAT/Enhancer binding protein β (C/EBPβ) is a transcription factor involved in numerous physiological as well as pathological conditions in the brain. However, little is known regarding its possible role in neurodegenerative disorders. We have… read more here.

Keywords: enhancer binding; ccaat enhancer; glial activation; parkinson disease ... See more keywords
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S-nitrosoglutathione inhibits adipogenesis in 3T3-L1 preadipocytes by S-nitrosation of CCAAT/enhancer-binding protein β

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Published in 2019 at "Scientific Reports"

DOI: 10.1038/s41598-019-51579-x

Abstract: Murine 3T3-L1 adipocytes share many similarities with primary fat cells and represent a reliable in vitro model of adipogenesis. The aim of this study was to probe the effect of S-nitrosoglutathione (GSNO) on adipocyte differentiation.… read more here.

Keywords: protein; ccaat enhancer; nitrosoglutathione; enhancer binding ... See more keywords
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CCAAT/Enhancer-Binding Protein Delta Regulates Glioblastoma Survival through Catalase-Mediated Hydrogen Peroxide Clearance

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Published in 2022 at "Oxidative Medicine and Cellular Longevity"

DOI: 10.1155/2022/4081380

Abstract: It has long been documented that cancer cells show increased and persistent oxidative stress due to increased reactive oxygen species (ROS), which is necessary for their increased proliferative rate. Due to the high levels of… read more here.

Keywords: hydrogen peroxide; binding protein; protein delta; ccaat enhancer ... See more keywords
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Lipase family member N is a novel target gene for CCAAT/enhancer-binding protein α in type 2 diabetic model mouse liver.

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Published in 2022 at "Endocrine journal"

DOI: 10.1507/endocrj.ej21-0465

Abstract: CCAAT/enhancer-binding protein α (C/EBPα) is a transcription factor abundantly expressed in the liver and white adipose tissue (WAT). In this study, we investigated the mechanism by which C/EBPα regulates the lipase family member N (Lipn)… read more here.

Keywords: binding protein; mouse; ccaat enhancer; type ... See more keywords
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CCAAT/Enhancer-Binding Protein Alpha Is a Novel Regulator of Vascular Smooth Muscle Cell Osteochondrogenic Transition and Vascular Calcification

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Published in 2022 at "Frontiers in Physiology"

DOI: 10.3389/fphys.2022.755371

Abstract: Aims Vascular calcification is a common clinical complication of chronic kidney disease (CKD), atherosclerosis (AS), and diabetes, which is associated with increased cardiovascular morbidity and mortality in patients. The transdifferentiation of vascular smooth muscle cells… read more here.

Keywords: ccaat enhancer; vascular smooth; enhancer binding; smooth muscle ... See more keywords
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[Progress of human CCAAT/enhancer binding protein epsilon on inflammation and infection].

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Published in 2019 at "Zhonghua wei zhong bing ji jiu yi xue"

DOI: 10.3760/cma.j.issn.2095-4352.2019.10.022

Abstract: OBJECTIVE Inflammation and infection are main causes of death in critically ill patients. But traditional treatment are non-comprehensive and limited. Human CCAAT/enhancer binding protein epsilon (C/EBPε) is a key transcription factor regulating the terminal differentiation… read more here.

Keywords: ccaat enhancer; infection; inflammation infection; enhancer binding ... See more keywords
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CCAAT/enhancer binding protein β Induces Post-Switched B Cells to Produce Blimp1 and Differentiate into Plasma Cells

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Published in 2020 at "Immune Network"

DOI: 10.4110/in.2020.20.e42

Abstract: Long-lasting post-switched plasma cells (PCs) arise mainly from germinal center (GC) reactions, but little is known about the mechanism by which GC B cells differentiate into PCs. Based on our observation that the expression of… read more here.

Keywords: protein; ccaat enhancer; post switched; plasma cells ... See more keywords