Articles with "ccat1" as a keyword



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lncRNA CCAT1 Promotes Glioma Tumorigenesis by Sponging miR‐181b

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Published in 2017 at "Journal of Cellular Biochemistry"

DOI: 10.1002/jcb.26116

Abstract: Colon cancer‐associated transcript 1 (CCAT1), a long non‐coding RNA (lncRNA), is upregulated and has a vital role in the pathogenesis of numerous cancers. Recently, its high expression was found in glioma tissues. miR‐181b is downregulated… read more here.

Keywords: promotes glioma; ccat1; expression; ccat1 promotes ... See more keywords
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LncRNA CCAT1 Protects Astrocytes Against OGD/R-Induced Damage by Targeting the miR-218/NFAT5-Signaling Axis

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Published in 2020 at "Cellular and Molecular Neurobiology"

DOI: 10.1007/s10571-020-00824-3

Abstract: Spinal cord injury (SCI) is a grievous neurology-related disorder that causes many devastating symptoms. Emerging roles of long non-coding RNAs (lncRNA) have been shown to play critical roles in multiple neurological diseases. This research planned… read more here.

Keywords: mir 218; astrocytes ogd; 218 nfat5; lncrna ccat1 ... See more keywords
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Long non-coding RNA CCAT1 promotes non-small cell lung cancer progression by regulating the miR-216a-5p/RAP2B axis

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Published in 2020 at "Experimental Biology and Medicine"

DOI: 10.1177/1535370220961013

Abstract: The long non-coding RNA colon cancer-associated transcript 1 (CCAT1) has been investigated to involve in the progression of non-small cell lung cancer (NSCLC). Thus, this study aims to explore the detailed molecular mechanisms of CCAT1… read more here.

Keywords: 216a rap2b; mir 216a; ccat1; progression ... See more keywords
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The lncRNA CCAT1 upregulates TGFβR1 via sponging miR-490-3p to promote TGFβ1-induced EMT of ovarian cancer cells

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Published in 2018 at "Cancer Cell International"

DOI: 10.1186/s12935-018-0604-1

Abstract: BackgroundOvarian cancer is the fifth leading cause of cancer deaths in women worldwide. LncRNACCAT1 was reported to play a critical role in cell metastasis of ovarian cancer. However, little is known about the detailed mechanism… read more here.

Keywords: mir 490; ccat1; ovarian cancer; tgf induced ... See more keywords
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Self-assembled fluorescent hybrid nanoparticles-mediated collaborative lncRNA CCAT1 silencing and curcumin delivery for synchronous colorectal cancer theranostics

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Published in 2021 at "Journal of Nanobiotechnology"

DOI: 10.1186/s12951-021-00981-7

Abstract: Background Cancer synergistic therapy strategy in combination with therapeutic gene and small molecule drug offers the possibility to amplify anticancer efficiency. Colon cancer-associated transcript-1 (CCAT1) is a well identified oncogenic long noncoding RNA (lncRNA) exerting… read more here.

Keywords: lncrna ccat1; ccat1; hybrid nanoparticles; colorectal cancer ... See more keywords

Long noncoding RNA CCAT1 functions as a ceRNA to antagonize the effect of miR-410 on the down-regulation of ITPKB in human HCT-116 and HCT-8 cells

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Published in 2017 at "Oncotarget"

DOI: 10.18632/oncotarget.21612

Abstract: Colorectal cancer is one of the most common malignancies, which has seriously affected people's health. Abnormal expression of long non-coding RNAs and microRNAs are closely related to the process of occurrence, development, invasion and metastasis… read more here.

Keywords: itpkb; ccat1; human hct; lnc ccat1 ... See more keywords

Long non-coding RNA CCAT1 as a diagnostic and prognostic molecular marker in various cancers: a meta-analysis

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Published in 2018 at "Oncotarget"

DOI: 10.18632/oncotarget.24923

Abstract: Purpose Long non-coding RNA colon cancer-associated transcript-1 (CCAT1) is newly found to be related with diagnoses and prognosis of cancer. This meta-analysis was performed to investigate the relationship between CCAT1 expression and clinical parameters, including… read more here.

Keywords: node metastasis; analysis; ccat1; 001 fix ... See more keywords
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LncRNA CCAT1 Promotes Colorectal Cancer Tumorigenesis Via A miR-181b-5p/TUSC3 Axis

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Published in 2019 at "OncoTargets and therapy"

DOI: 10.2147/ott.s216718

Abstract: Aim The aim was to determine the function and molecular mechanism of long non-coding RNA colon cancer associated transcript-1(lncRNA CCAT1) in the development of colorectal cancer (CRC). Methods CCAT1 mRNA expression levels were determined in… read more here.

Keywords: lncrna ccat1; ccat1; crc; colorectal cancer ... See more keywords
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The lncRNA CCAT1 Upregulates Proliferation and Invasion in Melanoma Cells via Suppressing miR-33a.

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Published in 2018 at "Oncology research"

DOI: 10.3727/096504017x14920318811749

Abstract: It is increasingly evident that various long noncoding RNAs (lncRNAs) participate in the tumorigenesis of multiple tumors, including melanoma. lncRNAs have been validated as oncogenic factors in various tumors; however, the potential regulatory mechanism of… read more here.

Keywords: melanoma; invasion; ccat1 melanoma; lncrna ccat1 ... See more keywords