The High Mutational Sensitivity of ccdA Antitoxin Is Linked to Codon Optimality
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DOI: 10.1093/molbev/msac187
Abstract: Deep mutational scanning studies suggest that synonymous mutations are typically silent and that most exposed, non active-site residues are tolerant to mutations. Here we show that the ccdA antitoxin component of the E.coli ccdAB toxin-antitoxin… read more here.
Keywords: mutational sensitivity; ccda antitoxin; high mutational; antitoxin ... See more keywords