The outer dynein arm assembly factor CCDC103 forms molecular scaffolds through multiple selfâinteraction sites
Sign Up to like & getrecommendations! Published in 2019 at "Cytoskeleton"
DOI: 10.1002/cm.21591
Abstract: CCDC103 is a small protein with unusual biophysical properties that is required for outer dynein arm assembly on ciliary axonemes. Mutations in both human and zebrafish CCDC103 proteins lead to primary ciliary dyskinesia. Previous studies… read more here.
Keywords: arm assembly; interaction; outer dynein; ccdc103 ... See more keywords
A recurrent homozygous missense mutation in CCDC103 causes asthenoteratozoospermia due to disorganized dynein arms
Sign Up to like & getrecommendations! Published in 2022 at "Asian Journal of Andrology"
DOI: 10.4103/aja2021122
Abstract: Asthenoteratozoospermia is one of the most severe types of qualitative sperm defects. Most cases are due to mutations in genes encoding the components of sperm flagella, which have an ultrastructure similar to that of motile… read more here.
Keywords: recurrent homozygous; dynein arms; dynein; ccdc103 ... See more keywords