Autophagy takes the STING out of DNA sensing
Sign Up to like & getrecommendations! Published in 2021 at "Cellular and Molecular Immunology"
DOI: 10.1038/s41423-021-00797-3
Abstract: The innate immune system has evolved to detect molecular signatures associated with invading microbes and the cellular damage these microbes cause. Recognition of microbial genomes, particularly those of intracellular microbes such as viruses, is crucial… read more here.
Keywords: dna; expression; ifn; infection ... See more keywords
The regulation of NLRP3 inflammasome activation by CCDC50-mediated autophagy
Sign Up to like & getrecommendations! Published in 2022 at "Autophagy"
DOI: 10.1080/15548627.2022.2080957
Abstract: ABSTRACT The assembly of the NLRP3 inflammasome can be initiated by a wide range of stimuli including exogenous infection as well as endogenous damage. Therefore, the tight regulation of the NLRP3 inflammasome is crucial for… read more here.
Keywords: inflammation; ccdc50; autophagy regulation; regulation nlrp3 ... See more keywords