The centriolar satellite protein CCDC66 interacts with CEP290 and functions in cilium formation and trafficking
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Cell Science"
DOI: 10.1242/jcs.196832
Abstract: ABSTRACT Centriolar satellites are membrane-less structures that localize and move around the centrosome and cilium complex in a microtubule-dependent manner. They play important roles in centrosome- and cilium-related processes, including protein trafficking to the centrosome… read more here.
Keywords: protein; centriolar satellite; cilium; ccdc66 ... See more keywords
The ciliopathy protein CCDC66 controls mitotic progression and cytokinesis by promoting microtubule nucleation and organization
Sign Up to like & getrecommendations! Published in 2022 at "PLoS Biology"
DOI: 10.1371/journal.pbio.3001708
Abstract: Precise spatiotemporal control of microtubule nucleation and organization is critical for faithful segregation of cytoplasmic and genetic material during cell division and signaling via the primary cilium in quiescent cells. Microtubule-associated proteins (MAPs) govern assembly,… read more here.
Keywords: nucleation; ccdc66; nucleation organization; microtubule nucleation ... See more keywords