Accurate quantitation of circulating cell-free mitochondrial DNA in plasma by droplet digital PCR
Sign Up to like & getrecommendations! Published in 2017 at "Analytical and Bioanalytical Chemistry"
DOI: 10.1007/s00216-017-0217-x
Abstract: AbstractTo establish a method for accurate quantitation of circulating cell-free mitochondrial DNA (ccf-mtDNA) in plasma by droplet digital PCR (ddPCR), we designed a ddPCR method to determine the copy number of ccf-mtDNA by amplifying mitochondrial… read more here.
Keywords: plasma; ccf mtdna; cell free; mtdna ... See more keywords
Altered levels of circulating mitochondrial DNA in elderly people with sarcopenia: Association with mitochondrial impairment
Sign Up to like & getrecommendations! Published in 2022 at "Experimental Gerontology"
DOI: 10.1016/j.exger.2022.111802
Abstract: BACKGROUND Age-related chronic inflammatory process is often referred to as "inflammaging", which had been described in several human disorders, including sarcopenia. Recently, mitochondrial DNA (MtDNA) has moved into the spotlight as a "damage-associated molecular pattern"… read more here.
Keywords: ccf mtdna; levels circulating; mtdna; mitochondrial dna ... See more keywords
Intra-individual state-dependent comparison of plasma mitochondrial DNA copy number and IL-6 levels in patients with bipolar disorder.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of affective disorders"
DOI: 10.1016/j.jad.2021.10.098
Abstract: BACKGROUND Patients with bipolar disorder (BD) have increased plasma IL-6 levels, which are higher in depressed BD (dBD) than remitted BD (rBD). However, the mechanism that differentiates the cytokine levels between dBD and rBD is… read more here.
Keywords: plasma ccf; plasma; mtdna; ccf mtdna ... See more keywords