Association of clinical outcomes in metastatic breast cancer patients with circulating tumour cell and circulating cell-free DNA.
Sign Up to like & getrecommendations! Published in 2019 at "European journal of cancer"
DOI: 10.1016/j.ejca.2018.10.012
Abstract: BACKGROUND Both circulating tumour cell (CTC) and total circulating cell-free DNA (ccfDNA) predict cancer patient prognosis. However, no study has explored the prognostic value of the combined use of CTC and ccfDNA. We aimed to… read more here.
Keywords: risk; ctc ccfdna; fold increased; ccfdna ... See more keywords
Dutch National Round Robin Trial on Plasma-Derived Circulating Cell-Free DNA Extraction Methods Routinely Used in Clinical Pathology for Molecular Tumor Profiling.
Sign Up to like & getrecommendations! Published in 2022 at "Clinical chemistry"
DOI: 10.1093/clinchem/hvac069
Abstract: BACKGROUND Efficient recovery of circulating tumor DNA (ctDNA) depends on the quantity and quality of circulating cell-free DNA (ccfDNA). Here, we evaluated whether various ccfDNA extraction methods routinely applied in Dutch laboratories affect ccfDNA yield,… read more here.
Keywords: dna; ccfdna; extraction; pathology ... See more keywords
Circulating cell-free double-stranded DNA and metabolic derangements in idiopathic pulmonary fibrosis: a new association
Sign Up to like & getrecommendations! Published in 2021 at "Thorax"
DOI: 10.1136/thoraxjnl-2021-218192
Abstract: The study by Whalen et al has delineated the association between circulating cellfree DNA (ccfDNA) and metabolic derangements in idiopathic pulmonary fibrosis (IPF). They examined healthy controls compared with slow and rapid progressors. The latter… read more here.
Keywords: dna; ccfdna; derangements idiopathic; idiopathic pulmonary ... See more keywords
Abstract 780: Digital PCR-based EGFR T790M mutation detection from human blood samples collected in PAXgene Blood ccfDNA Tubes
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-780
Abstract: Introduction: Circulating cell-free DNA (ccfDNA) is used as an analyte in liquid biopsy-based cancer research with promising applications in the fields of cancer screening, therapeutic decision making and monitoring and minimal residual disease control. However,… read more here.
Keywords: blood ccfdna; ccfdna; blood; mutation ... See more keywords
Automated size selection for short cell-free DNA fragments enriches for circulating tumor DNA and improves error correction during next generation sequencing
Sign Up to like & getrecommendations! Published in 2018 at "PLoS ONE"
DOI: 10.1371/journal.pone.0197333
Abstract: Circulating tumor-derived cell-free DNA (ctDNA) enables non-invasive diagnosis, monitoring, and treatment susceptibility testing in human cancers. However, accurate detection of variant alleles, particularly during untargeted searches, remains a principal obstacle to widespread application of cell-free… read more here.
Keywords: dna; ccfdna; free dna; cell free ... See more keywords