Investigating the effect of ribavirin treatment on genetic mutations in Crimean–Congo haemorrhagic fever virus (CCHFV) through next‐generation sequencing
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Medical Virology"
DOI: 10.1002/jmv.28548
Abstract: Crimean–Congo haemorrhagic fever (CCHF) is the most widespread tick‐borne viral haemorrhagic fever affecting humans, and yet a licensed drug against the virus (CCHFV) is still not available. While several studies have suggested the efficacy of… read more here.
Keywords: ribavirin; haemorrhagic fever; effect; cchfv ... See more keywords
Expression and characterization of codon-optimized Crimean-Congo hemorrhagic fever virus Gn glycoprotein in insect cells
Sign Up to like & getrecommendations! Published in 2017 at "Archives of Virology"
DOI: 10.1007/s00705-017-3315-3
Abstract: Crimean-Congo hemorrhagic fever virus (CCHFV) is a major cause of tick-borne viral hemorrhagic disease in the world. Despite of its importance as a deadly pathogen, there is currently no licensed vaccine against CCHF disease. The… read more here.
Keywords: hemorrhagic; cchfv; expression; congo hemorrhagic ... See more keywords
Isolation, Characterization, and Phylogenetic Analysis of Two New Crimean-Congo Hemorrhagic Fever Virus Strains from the Northern Region of Xinjiang Province, China
Sign Up to like & getrecommendations! Published in 2018 at "Virologica Sinica"
DOI: 10.1007/s12250-018-0020-7
Abstract: Crimean-Congo hemorrhagic fever (CCHF) caused by the CCHF virus (CCHFV) is a tick-borne natural focal disease with a mortality rate of approximately 50%. CCHFV is widely prevalent in Africa, southern Asia, the Middle East, and… read more here.
Keywords: cchfv strains; xinjiang; cchfv; xinjiang province ... See more keywords
Identification of 2′‐deoxy‐2′‐fluorocytidine as a potent inhibitor of Crimean‐Congo hemorrhagic fever virus replication using a recombinant fluorescent reporter virus
Sign Up to like & getrecommendations! Published in 2017 at "Antiviral Research"
DOI: 10.1016/j.antiviral.2017.10.008
Abstract: Abstract Crimean‐Congo hemorrhagic fever virus (CCHFV), a tick‐borne orthonairovirus, causes a severe hemorrhagic disease in humans (Crimean‐Congo hemorrhagic fever, CCHF). Currently, no vaccines are approved to prevent CCHF; treatment is limited to supportive care and… read more here.
Keywords: reporter; cchfv; virus; identification ... See more keywords
Protective neutralizing antibodies from human survivors of Crimean-Congo hemorrhagic fever
Sign Up to like & getrecommendations! Published in 2021 at "Cell"
DOI: 10.1016/j.cell.2021.05.001
Abstract: Crimean-Congo hemorrhagic fever virus (CCHFV) is a World Health Organization priority pathogen. CCHFV infections cause a highly lethal hemorrhagic fever for which specific treatments and vaccines are urgently needed. Here, we characterize the human immune… read more here.
Keywords: hemorrhagic; hemorrhagic fever; cchfv; protective neutralizing ... See more keywords
Single dose VSV-based vaccine protects mice against lethal heterologous Crimean-Congo hemorrhagic fever virus challenge
Sign Up to like & getrecommendations! Published in 2025 at "NPJ Vaccines"
DOI: 10.1038/s41541-025-01164-3
Abstract: Crimean-Congo hemorrhagic fever virus (CCHFV) causes a severe, sometimes fatal hemorrhagic fever (CCHF) in humans. Currently, there are no approved therapies against CCHF. In this study we used the recombinant vesicular stomatitis virus (VSV) platform… read more here.
Keywords: hemorrhagic fever; virus; vsv; vaccine ... See more keywords
Purification of Crimean–Congo hemorrhagic fever virus nucleoprotein and its utility for serological diagnosis
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-81752-0
Abstract: Crimean–Congo hemorrhagic fever virus (CCHFV) causes a zoonotic disease, Crimean–Congo hemorrhagic fever (CCHF) endemic in Africa, Asia, the Middle East, and Southeastern Europe. However, the prevalence of CCHF is not monitored in most of the… read more here.
Keywords: hemorrhagic fever; congo hemorrhagic; cchfv; crimean congo ... See more keywords
Immunogenicity of NSDV GP38 and the role of furin in GP38 proteolytic processing
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Virology"
DOI: 10.1128/jvi.00537-25
Abstract: ABSTRACT Nairobi sheep disease virus (NSDV) is a tick-borne orthonairovirus, which is genetically related to Crimean-Congo hemorrhagic fever virus (CCHFV), and causes severe hemorrhagic gastroenteritis in infected sheep. CCHFV GP38, a cleavage product of the… read more here.
Keywords: role; gp38; nsdv gp38; immunogenicity nsdv ... See more keywords
Nucleoside-modified mRNA vaccines protect IFNAR-/- mice against Crimean Congo hemorrhagic fever virus infection.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of virology"
DOI: 10.1128/jvi.01568-21
Abstract: Crimean-Congo hemorrhagic fever (CCHF), caused by Crimean-Congo hemorrhagic fever virus (CCHFV), is on the World Health Organizations' list of prioritized diseases and pathogens. With global distribution, high fatality rate and no approved vaccine or effective… read more here.
Keywords: fever; hemorrhagic fever; infection; cchfv ... See more keywords
Crimean–Congo Hemorrhagic Fever Virus Infections in Slaughtered Camels and Abattoir Workers in the United Arab Emirates
Sign Up to like & getrecommendations! Published in 2025 at "Transboundary and Emerging Diseases"
DOI: 10.1155/tbed/3409106
Abstract: Crimean–Congo hemorrhagic fever (CCHF) is a tick-borne disease caused by the CCHF virus (CCHFV) and is characterized by the sudden onset of high fever and hemorrhagic manifestations. This study aimed to estimate the seroprevalence of… read more here.
Keywords: camels abattoir; fever; hemorrhagic; anti cchfv ... See more keywords
Zoonotic arbovirus infections in cattle in Mozambique with special reference to Crimean-Congo hemorrhagic fever virus (CCHFV) and rift valley fever virus (RVFV)
Sign Up to like & getrecommendations! Published in 2025 at "Virology Journal"
DOI: 10.1186/s12985-025-02804-9
Abstract: Arboviruses pose a great threat to public health in sub-Saharan African countries. Mozambique is located in a region that is prone to climate change-related devastation, including heavy rainfalls and severe droughts that favor the emergence… read more here.
Keywords: rvfv; hemorrhagic fever; virus; fever virus ... See more keywords