Abstract 262: Gastrin-dependent suppression of CCK2R+ antrum stem cells inhibits gastric atrophy and cancer initiation in C57BL/6 mice
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DOI: 10.1158/1538-7445.am2024-262
Abstract: Background The cholecystokin-2/gastrin receptor (CCK2R) is expressed by rare epithelial cells in the gastric antrum that are bone fide +4 gastric stem cells. CCK2R+ antral stem cells are relatively quiescent, divide asymmetrically, and lineage trace… read more here.
Keywords: cancer; cck2r; stem; stem cells ... See more keywords