CCL17 exerts a neuroimmune modulatory function and is expressed in hippocampal neurons
Sign Up to like & getrecommendations! Published in 2018 at "Glia"
DOI: 10.1002/glia.23507
Abstract: Chemokines are important signaling molecules in the immune and nervous system. Using a fluorescence reporter mouse model, we demonstrate that the chemokine CCL17, a ligand of the chemokine receptor CCR4, is produced in the murine… read more here.
Keywords: hippocampal neurons; neuroimmune modulatory; exerts neuroimmune; ccl17 exerts ... See more keywords
Increased peripheral levels of TARC/CCL17 in first episode psychosis patients
Sign Up to like & getrecommendations! Published in 2019 at "Schizophrenia Research"
DOI: 10.1016/j.schres.2018.12.033
Abstract: BACKGROUND Evidence for a link between the pathophysiology of schizophrenia and the immune system is mounting. Altered levels of chemokines in plasma have previously been reported in patients with schizophrenia under antipsychotic medication. Here we… read more here.
Keywords: levels tarc; ccl17; first episode; tarc ccl17 ... See more keywords
CCL17/TARC in autoimmunity and inflammation - not just a T-cell chemokine.
Sign Up to like & getrecommendations! Published in 2023 at "Immunology and cell biology"
DOI: 10.1111/imcb.12644
Abstract: Chemokine (C-C) ligand 17 (CCL17) was first identified as thymus- and activation- regulated chemokine (TARC), when it was found to be constitutively expressed in the thymus and identified as a T-cell chemokine. This chemo-attractant molecule… read more here.
Keywords: tarc; cell chemokine; ccl17; biology ... See more keywords
CCL17 exerts neuroprotection through activation of CCR4/mTORC2 axis in microglia after subarachnoid haemorrhage in rats
Sign Up to like & getrecommendations! Published in 2022 at "Stroke and Vascular Neurology"
DOI: 10.1136/svn-2022-001659
Abstract: Background and purpose C-C motif chemokine ligand 17 (CCL17) presents an important role in immune regulation, which is critical in the pathophysiology of brain injury after subarachnoid haemorrhage (SAH). There is rare evidence to illustrate… read more here.
Keywords: mtorc2; ccr4 mtorc2; mtorc2 axis; ccl17 ... See more keywords
CCL17 Aggravates Myocardial Injury by Suppressing Recruitment of Regulatory T Cells
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DOI: 10.1161/circulationaha.121.055888
Abstract: Supplemental Digital Content is available in the text. Background: Recent studies have established that CCR2 (C-C chemokine receptor type 2) marks proinflammatory subsets of monocytes, macrophages, and dendritic cells that contribute to adverse left ventricle… read more here.
Keywords: myocardial inflammation; ccl17; dendritic cells; macrophages dendritic ... See more keywords
Role of CC Chemokine Ligand 17 in Mouse Models of Chronic Obstructive Pulmonary Disease.
Sign Up to like & getrecommendations! Published in 2022 at "American journal of respiratory cell and molecular biology"
DOI: 10.1165/rcmb.2021-0069oc
Abstract: Lung function deterioration is significantly associated with poor prognosis in patients with chronic obstructive pulmonary disease (COPD). We previously reported that CC chemokine ligand 17/thymus and activation-regulated chemokine (CCL17/TARC) could be a predictive factor of… read more here.
Keywords: role; chronic obstructive; cigarette; chemokine ligand ... See more keywords
Down-regulation of CCL17 in cancer-associated fibroblasts inhibits cell migration and invasion of breast cancer through ERK1/2 pathway
Sign Up to like & getrecommendations! Published in 2019 at "Cancer Management and Research"
DOI: 10.2147/cmar.s211651
Abstract: Objective Cancer-associated fibroblasts (CAFs) in the tumor microenvironment are involved in cancer development and progression, including breast cancer (BC). Up-regulation of CCL17 was observed in BC and predicted a decrease in overall survival, suggesting an… read more here.
Keywords: migration invasion; ccl17; cell; cancer ... See more keywords
CCL17 Promotes Colitis-Associated Tumorigenesis Dependent on the Microbiota.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of immunology"
DOI: 10.4049/jimmunol.2100867
Abstract: Colorectal cancer is one of the most common cancers and a major cause of mortality. Proinflammatory and antitumor immune responses play critical roles in colitis-associated colon cancer. CCL17, a chemokine of the C-C family and… read more here.
Keywords: promotes colitis; colitis associated; ccl17 promotes; mice ... See more keywords