CCL19 with CCL21‐tail displays enhanced glycosaminoglycan binding with retained chemotactic potency in dendritic cells
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Leukocyte Biology"
DOI: 10.1002/jlb.2vma0118-008r
Abstract: CCL19 is more potent than CCL21 in inducing chemotaxis of human dendritic cells (DC). This difference is attributed to 1) a stronger interaction of the basic C‐terminal tail of CCL21 with acidic glycosaminoglycans (GAGs) in… read more here.
Keywords: potency; ccl21 tail; ccl19 ccl21; tail ... See more keywords
Bulk and single-cell RNA-sequencing analyses revealed potential key genes and the role of CCL19/CCL21-CCR7 axis in hidradenitis suppurativa
Sign Up to like & getrecommendations! Published in 2025 at "PLOS One"
DOI: 10.1371/journal.pone.0322565
Abstract: Hidradenitis suppurativa (HS) is a chronic inflammatory skin disorder, affecting the pilosebaceous unit in apocrine gland-rich areas, characterized by painful nodules, abscesses and draining tunnels. The underlying molecular and immunological mechanisms remain poorly understood. This… read more here.
Keywords: role; ccl19 ccl21; ccr7 axis; ccr7 ... See more keywords