Abstract 5020: Therapeutic potential of an immune modulatory CCL22-based vaccine
Sign Up to like & getrecommendations! Published in 2019 at "Immunology"
DOI: 10.1158/1538-7445.am2019-5020
Abstract: CCL22 is a macrophage-derived chemokine that exerts immunosuppressive functions by the recruitment of regulatory T cells (Tregs) through the CCL22/CCR4 axis. It is expressed by cells in the tumor microenvironment (TME) in many different cancer… read more here.
Keywords: immune modulatory; cancer; tumor; ccl22 specific ... See more keywords
Abstract 5153: The role of CCL22-specific CD4 T cells in modulating the immunosuppressive tumor microenvironment in ovarian cancer
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-5153
Abstract: Background: CCL22, a macrophage-derived chemokine, is overexpressed in ovarian cancer and exerts immunosuppressive functions by the recruitment of regulatory T cells (Tregs) to the tumor microenvironment (TME). Our research group described naturally occurring T cells… read more here.
Keywords: ccl22 specific; ovarian cancer; ccl22; specific cd4 ... See more keywords