Hypoxia directed migration of human naïve monocytes is associated with an attenuation of cytokine release: indications for a key role of CCL26
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DOI: 10.1186/s12967-020-02567-7
Abstract: Background Numerous tissue-derived factors have been postulated to be involved in tissue migration of circulating monocytes. The aim of this study was to evaluate whether a defined hypoxic gradient can induce directed migration of naïve… read more here.
Keywords: human monocytes; migration; ccl26; hypoxia ... See more keywords
The Role of Heparan Sulfate in CCL26-Induced Eosinophil Chemotaxis
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DOI: 10.3390/ijms23126519
Abstract: Proinflammatory chemokine ligand 26 (CCL26, eotaxin-3) mediates transendothelial cell migration of eosinophils by binding and activating the G-protein-coupled (GPC) chemokine receptor 3 on the surface of eosinophilic cells. Here we have investigated the role of… read more here.
Keywords: ccl26 induced; heparan sulfate; eosinophil chemotaxis; ccl26 ... See more keywords