Cooperation between Constitutive and Inducible Chemokines Enables T Cell Engraftment and Immune Attack in Solid Tumors.
Sign Up to like & getrecommendations! Published in 2019 at "Cancer cell"
DOI: 10.1016/j.ccell.2019.05.004
Abstract: We investigated the role of chemokines in regulating T cell accumulation in solid tumors. CCL5 and CXCL9 overexpression was associated with CD8+ T cell infiltration in solid tumors. T cell infiltration required tumor cell-derived CCL5 and was amplified… read more here.
Keywords: solid tumors; cell infiltration; ccl5 expression; cell ... See more keywords
CCL5 is induced by TLR 3 signaling in HuCCT1 human biliary epithelial cells: possible involvement in the pathogenesis of biliary atresia.
Sign Up to like & getrecommendations! Published in 2017 at "Biomedical research"
DOI: 10.2220/biomedres.38.269
Abstract: Biliary atresia (BA) is a disease of the newborn that is characterized by progressive, inflammatory and sclerosing cholangiopathy. Innate immune responses to viral components are thought to be involved in the pathogenesis of BA. It… read more here.
Keywords: ccl5; human biliary; pathogenesis; biliary atresia ... See more keywords