Articles with "ccm disease" as a keyword



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Detection of p62/SQSTM1 Aggregates in Cellular Models of CCM Disease by Immunofluorescence.

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Published in 2020 at "Methods in molecular biology"

DOI: 10.1007/978-1-0716-0640-7_30

Abstract: Cerebral cavernous malformations (CCM) is a familial or sporadic rare disorder that is characterized by capillary vascular lesions with a mulberry-like appearance on MRI scans. Three distinct genes have been associated to CCM disease, known… read more here.

Keywords: p62 sqstm1; immunofluorescence; ccm disease; detection p62 ... See more keywords
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Spectrophotometric Method for Determining Glyoxalase 1 Activity in Cerebral Cavernous Malformation (CCM) Disease.

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Published in 2020 at "Methods in molecular biology"

DOI: 10.1007/978-1-0716-0640-7_33

Abstract: Glyoxalase 1 (Glo1) is a glutathione (GSH)-dependent enzyme that catalyzes the isomerization of the hemithioacetal formed non-enzymatically from methylglyoxal (MG) and GSH to S-D-lactoylglutathione (SLG). The activity of Glo1 is measured spectrophotometrically by following the… read more here.

Keywords: glyoxalase; ccm disease; malformation ccm; cerebral cavernous ... See more keywords