RhoA Kinase Inhibition With Fasudil Versus Simvastatin in Murine Models of Cerebral Cavernous Malformations
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DOI: 10.1161/strokeaha.116.015013
Abstract: Background and Purpose— We sought to compare the effect of chronic treatment with commonly tolerated doses of Fasudil, a specific RhoA kinase (ROCK) inhibitor, and simvastatin (with pleiotropic effects including ROCK inhibition) on cerebral cavernous… read more here.
Keywords: fasudil; simvastatin; rhoa kinase; ccm1 msh2 ... See more keywords