Circulating Wnt1-inducible signaling pathway protein-1 (WISP-1/CCN4) is a novel biomarker of adiposity in subjects with type 2 diabetes
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cell Communication and Signaling"
DOI: 10.1007/s12079-019-00536-4
Abstract: Background Wnt1-inducible signaling pathway protein 1, or cellular communication network factor 4 (CCN4), a member of CCN family of secreted, extracellular matrix associated signaling proteins, recently was validated as a novel adipose tissue derived cytokine.… read more here.
Keywords: wnt1 inducible; ccn4; signaling pathway; type diabetes ... See more keywords
Aneurysm severity is suppressed by deletion of CCN4
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Cell Communication and Signaling"
DOI: 10.1007/s12079-021-00623-5
Abstract: Patients with abdominal aortic aneurysms are frequently treated with high-risk surgery. A pharmaceutical treatment to reverse aneurysm progression could prevent the need for surgery and save both lives and healthcare resources. Since CCN4 regulates cell… read more here.
Keywords: ccn4; ccn4 apoe; deletion ccn4; apoe mice ... See more keywords
CCN4/WISP1 Promotes Migration of Human Primary Osteoarthritic Chondrocytes
Sign Up to like & getrecommendations! Published in 2022 at "Cartilage"
DOI: 10.1177/19476035221144747
Abstract: Objectives Previously, we have shown the involvement of cellular communication network factor 4/Wnt-activated protein Wnt-1-induced signaling protein 1 (CCN4/WISP1) in osteoarthritic (OA) cartilage and its detrimental effects on cartilage. Here, we investigated characteristics of CCN4… read more here.
Keywords: ccn4; cartilage; human primary; migration human ... See more keywords