CircNFIX promotes progression of pituitary adenoma via CCNB1 by sponging miR-34a -5p
Sign Up to like & getrecommendations! Published in 2021 at "Molecular and Cellular Endocrinology"
DOI: 10.1016/j.mce.2020.111140
Abstract: Previous studies have shown that CCNB1 affects the invasiveness of pituitary adenomas, and it is of great significance to find the upstream mechanism of regulating CCNB1.In this study, we explored a significantly overexpressed circRNA in… read more here.
Keywords: sponging mir; mir 34a; circnfix; pituitary adenomas ... See more keywords
CCNB1 promotes the development of hepatocellular carcinoma by mediating DNA replication in the cell cycle.
Sign Up to like & getrecommendations! Published in 2021 at "Experimental biology and medicine"
DOI: 10.1177/15353702211049149
Abstract: In our studies, cyclin B1 (CCNB1) mRNA and protein were overexpressed in hepatocellular carcinoma (HCC) tissues compared with non-HCC tissues. Moreover, CCNB1 was overexpressed in the serum of HCC patients. The expression of CCNB1 was… read more here.
Keywords: dna replication; ccnb1; hcc; cell cycle ... See more keywords
Circ-CCNB1 Modulates Trophoblast Proliferation and Invasion in Spontaneous Abortion by Regulating miR-223/SIAH1 axis
Sign Up to like & getrecommendations! Published in 2022 at "Endocrinology"
DOI: 10.1210/endocr/bqac093
Abstract: Abstract Context Spontaneous abortion (SA) is a common disorder in early pregnancy. Circular RNAs (circRNAs) have been reported to exert important regulatory effects on trophoblast function and embryo development. Objective The aim of this study… read more here.
Keywords: circ ccnb1; trophoblast proliferation; ccnb1; mir 223 ... See more keywords
Hsa-mir-3163 and CCNB1 may be potential biomarkers and therapeutic targets for androgen receptor positive triple-negative breast cancer
Sign Up to like & getrecommendations! Published in 2021 at "PLoS ONE"
DOI: 10.1371/journal.pone.0254283
Abstract: Breast cancer (BC) is the most common malignancy in female, but the role of androgen receptor (AR) in triple-negative breast cancer (TNBC) is still unclear. This study aimed to exam the performance of innovative biomarkers… read more here.
Keywords: cancer; hsa mir; ccnb1; mir 3163 ... See more keywords
Positive Feedback Stimulation of Ccnb1 and Mos mRNA Translation by MAPK Cascade During Mouse Oocyte Maturation
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2020.609430
Abstract: In mammalian species, both the maturation promoting factor (MPF) and the mitogen-activated protein kinase (MAPK) cascade play critical roles in modulating oocyte meiotic cell-cycle progression. MPF is a critical heterodimer composed of CDK1 and cyclin… read more here.
Keywords: oocyte maturation; mrna translation; ccnb1; translation ... See more keywords
Cyclin B1 expression as an independent prognostic factor for lung adenocarcinoma and its potential pathways
Sign Up to like & getrecommendations! Published in 2022 at "Oncology Letters"
DOI: 10.3892/ol.2022.13561
Abstract: Although great progress has been made in the early diagnosis and targeted therapy of lung adenocarcinoma (LUAD), the survival of patients with LUAD remains unsatisfactory. There is an urgent requirement for new biomarkers to guide… read more here.
Keywords: ccnb1; patients luad; lung adenocarcinoma; expression ... See more keywords
Polymorphisms of CCNB1 Associated With the Clinical Outcomes of Platinum-Based Chemotherapy in Chinese NSCLC Patients
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DOI: 10.7150/jca.21151
Abstract: As a crucial cell cycle regulator and G2/M phase promotor, CCNB1 played an essential role in progression of chemotherapy related cell death. Platinum-based chemotherapy is still the first-line chemotherapy regimen for most advanced NSCLC patients.… read more here.
Keywords: chemotherapy; platinum based; nsclc patients; advanced nsclc ... See more keywords