hsa_circ_0062389 promotes the progression of non-small cell lung cancer by sponging miR-103a-3p to mediate CCNE1 expression.
Sign Up to like & getrecommendations! Published in 2019 at "Cancer genetics"
DOI: 10.1016/j.cancergen.2019.12.004
Abstract: Recently, increasing evidence showed that circular RNAs (circRNAs) play critical roles in tumor progression. However, the roles of hsa_circ_0062389 in non-small cell lung cancer (NSCLC) development remain unclear. In the present study, hsa_circ_0062389 expression was… read more here.
Keywords: circ 0062389; ccne1; mir 103a; lung cancer ... See more keywords
Targeting CCNE1 amplified ovarian and endometrial cancers by combined inhibition of PKMYT1 and ATR
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DOI: 10.1038/s41467-025-58183-w
Abstract: Ovarian cancers (OVCAs) and endometrial cancers (EMCAs) with CCNE1-amplification are often resistant to standard treatment and represent an unmet clinical need. Synthetic-lethal screening identified loss of the CDK1 regulator, PKMYT1, as synthetically lethal with CCNE1-amplification.… read more here.
Keywords: ccne1; ovarian endometrial; pkmyt1; endometrial cancers ... See more keywords
The role of long non-coding RNA LINC00839 in oral squamous cell carcinoma based on bioinformatics and experimental research
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DOI: 10.1038/s41598-024-82922-6
Abstract: This study explores the role of LINC00839 and its potential interaction with the miR-195-5p/cyclin E1 (CCNE1) axis in oral squamous cell carcinoma (OSCC). Using The Cancer Genome Atlas, we analyzed lncRNA, miRNA, and mRNA sequencing… read more here.
Keywords: ccne1; cell carcinoma; oral squamous; squamous cell ... See more keywords
CCNE1 is a potential target of Metformin for tumor suppression of ovarian high-grade serous carcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Cell Cycle"
DOI: 10.1080/15384101.2022.2109362
Abstract: ABSTRACT High-grade serous ovarian cancer (HGSOC) is the most common and malignant type of ovarian cancer, accounting for 70%–80% of mortality. However, the treatment of HGSOC has improved little in the past few decades. Metformin… read more here.
Keywords: target metformin; hgsoc; ccne1; treatment ... See more keywords
Long Non‐Coding RNA LINC01116 Promotes the Proliferation of Lung Adenocarcinoma by Targeting miR‐9‐5p/CCNE1 Axis
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DOI: 10.1111/jcmm.70270
Abstract: Long non‐coding RNA (lncRNA) LINC01116 is crucial in promoting cell proliferation, invasion and migration in solid tumours, including lung adenocarcinoma (LUAD). LINC01116 acts as a competing endogenous RNAs (ceRNA) that binds competitively to microRNAs and… read more here.
Keywords: ccne1; long non; rna; cell ... See more keywords
MEG3 LncRNA from Exosomes Released from Cancer-Associated Fibroblasts Enhances Cisplatin Chemoresistance in SCLC via a MiR-15a-5p/CCNE1 Axis
Sign Up to like & getrecommendations! Published in 2022 at "Yonsei Medical Journal"
DOI: 10.3349/ymj.2022.63.3.229
Abstract: Purpose Long non-coding RNAs (lncRNAs) may act as oncogenes in small-cell lung cancer (SCLC). Exosomes containing lncRNAs released from cancer-associated fibroblasts (CAF) accelerate tumorigenesis and confer chemoresistance. This study aimed to explore the action mechanism… read more here.
Keywords: cell; sclc; mir 15a; ccne1 ... See more keywords