Targeting the CCL2-CCR2 axis for atheroprotection.
Sign Up to like & getrecommendations! Published in 2022 at "European heart journal"
DOI: 10.1093/eurheartj/ehac094
Abstract: Decades of research have established atherosclerosis as an inflammatory disease. Only recently though, clinical trials provided proof-of-concept evidence for the efficacy of anti-inflammatory strategies with respect to cardiovascular events, thus offering a new paradigm for… read more here.
Keywords: targeting ccl2; axis atheroprotection; ccr2; ccl2 ccr2 ... See more keywords
Role of the CCL2-CCR2 axis in cardiovascular disease: Pathogenesis and clinical implications
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.975367
Abstract: The CCL2-CCR2 axis is one of the major chemokine signaling pathways that has received special attention because of its function in the development and progression of cardiovascular disease. Numerous investigations have been performed over the… read more here.
Keywords: cardiovascular disease; ccl2 ccr2; ccl2; ccr2 axis ... See more keywords
CCL2/CCR2 axis induces hepatocellular carcinoma invasion and epithelial-mesenchymal transition in vitro through activation of the Hedgehog pathway
Sign Up to like & getrecommendations! Published in 2018 at "Oncology Reports"
DOI: 10.3892/or.2017.6069
Abstract: Chemokine (C-C motif) ligand 2 (CCL2) has been shown to play an important role in the regulation of tumor cell growth, metastasis and host immune response. CCL2 preferentially binds to the C-C chemokine receptor type… read more here.
Keywords: cell; invasion; ccl2; ccr2 axis ... See more keywords