Elevated Mast Cell Abundance is Associated with Enrichment of CCR2+ Cytotoxic T cells and Favorable Prognosis in Lung Adenocarcinoma.
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DOI: 10.1158/0008-5472.can-22-3140
Abstract: Mast cells constitute indispensable immunoregulatory sentinel cells in the tumor microenvironment. A better understanding of the regulation and functions of mast cells in lung adenocarcinoma (LUAD) could uncover therapeutic approaches to reprogram the immunosuppressive tumor… read more here.
Keywords: cell; lung adenocarcinoma; favorable prognosis; mast ... See more keywords
Abstract 5940: Enhanced mast cell abundance is associated with the enrichment of CCR2+ cytotoxic T cells and favorable prognosis in lung adenocarcinoma
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-5940
Abstract: Mast cells constitute indispensably immunoregulatory sentinel cells in tumor microenvironment, however, their functions are poorly characterized in lung adenocarcinoma (LUAD). Here, we performed flow cytometry and single-cell RNA sequencing to comprehensively characterize LUAD infiltrating MCs.… read more here.
Keywords: lung adenocarcinoma; ccr2; favorable prognosis; mast ... See more keywords