Distinct macrophage subsets in the human heart
Sign Up to like & getrecommendations! Published in 2018 at "Nature Reviews Cardiology"
DOI: 10.1038/s41569-018-0053-5
Abstract: The human heart contains CC chemokine receptor type 2 (CCR2)+ and CCR2 macrophage subsets with distinct origins and functions, similar to the macrophage heterogeneity found in mouse hearts. Investigators used transmural left ventricular (LV) myocardial… read more here.
Keywords: human heart; heart; ccr2 macrophages; macrophage subsets ... See more keywords
CCR2+ Macrophages Promote Orthodontic Tooth Movement and Alveolar Bone Remodeling
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.835986
Abstract: During mechanical force-induced alveolar bone remodeling, macrophage-mediated local inflammation plays a critical role. Yet, the detailed heterogeneity of macrophages is still unknown. Single-cell RNA sequencing was used to study the transcriptome heterogeneity of macrophages during… read more here.
Keywords: alveolar bone; ccr2 macrophages; bone; orthodontic tooth ... See more keywords