Articles with "ccr3" as a keyword



Macrophage-Derived CCL24 Promotes Cardiac Fibrosis Via Fibroblast CCR3

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Published in 2025 at "Circulation Research"

DOI: 10.1161/circresaha.125.326599

Abstract: BACKGROUND: Inflammation is a significant risk factor and contributor to the development of cardiovascular disease by driving adaptive and maladaptive responses to cardiac injury. Macrophages are the most abundant immune cells in the heart and… read more here.

Keywords: receptor; cardiac function; heart; fibroblast ... See more keywords

Predictive value of CCL26 and CCR3 levels for prognosis assessment in children with Mycoplasma pneumoniae pneumonia treated with azithromycin

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Published in 2025 at "Translational Pediatrics"

DOI: 10.21037/tp-2025-296

Abstract: Background Mycoplasma pneumoniae pneumonia (MPP), a prevalent form of community-acquired pneumonia (CAP) in schoolchildren, frequently results in persistent fever or complications in 15–25% of cases despite azithromycin treatment. This highlights the urgent need for novel… read more here.

Keywords: ccr3 levels; ccl26 ccr3; ccr3; mycoplasma pneumoniae ... See more keywords

CCR3 Is Associated with the Death of a Photoreceptor Cell-line Induced by Light Exposure

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Published in 2017 at "Frontiers in Pharmacology"

DOI: 10.3389/fphar.2017.00207

Abstract: The C-C chemokine receptor type 3 (CCR3) is the receptor for eotaxins (CCL-11, 24, 26), RANTES (CCL-5) and MCP-3 (CCL-7). It was reported that an inhibition of CCR3 by antagonists or antibodies reduces the degree… read more here.

Keywords: ccr3; death; induced light; cell ... See more keywords

C-C chemokine receptor type 3 gene knockout alleviates inflammatory responses in allergic rhinitis model mice by regulating the expression of eosinophil granule proteins and immune factors

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Published in 2018 at "Molecular Medicine Reports"

DOI: 10.3892/mmr.2018.9380

Abstract: The present study aimed to investigate the effects of C-C chemokine receptor type 3 (CCR3) gene knockout on allergic rhinitis (AR) in mice, as well as the underlying molecular mechanisms. Ovalbumin was administrated to CCR3+/+… read more here.

Keywords: ccr3; model; expression; gene knockout ... See more keywords

CD34+ PI16+ fibroblast progenitors aggravate neointimal lesions of allograft arteries via CCL11/CCR3-PI3K/AKT pathway

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Published in 2025 at "Theranostics"

DOI: 10.7150/thno.104650

Abstract: Rationale: Transplant-accelerated arteriosclerosis is a common complication that limits the long-term survival of organ transplant recipients. While previous studies have indicated the involvement of CD34+ stem/progenitor cells (SPCs) in this process, their heterogeneity and potential… read more here.

Keywords: ccl11; cd34 pi16; fibroblast progenitors; ccr3 ... See more keywords