Genetic polymorphisms of CCL5 and CCR5 to predict efficacy of cetuximab-based treatment in metastatic colorectal cancer patients depending on primary tumor location.
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DOI: 10.1200/jco.2017.35.15_suppl.3594
Abstract: 3594Background: EGFR signaling blockade increases CCL5 expression, which attracts with tumor-infiltrating leukocytes regulating either the host-derived anti-tumor immunity or tumor progression. We ... read more here.
Keywords: genetic polymorphisms; predict efficacy; polymorphisms ccl5; ccr5 predict ... See more keywords