CCR7 signalosomes are pre-assembled on tips of lymphocyte microvilli in proximity to LFA-1.
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DOI: 10.1016/j.bpj.2021.08.014
Abstract: Leukocyte microvilli are elastic actin-rich projections implicated in rapid sensing and penetration across glycocalyx barriers. Microvilli are critical for the capture and arrest of flowing lymphocytes by high endothelial venules (HEVs), the main lymph node… read more here.
Keywords: lymphocyte microvilli; lfa; lfa molecules; ccr7 ... See more keywords