miR‐122 promotes metastasis of clear‐cell renal cell carcinoma by downregulating Dicer
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DOI: 10.1002/ijc.31050
Abstract: Although overall downregulation of microRNAs (miRNAs) is a general feature of clear‐cell renal cell carcinoma (ccRCC), several miRNAs are consistently upregulated, among which miR‐122 was markedly increased in ccRCC tissues. Our study aims to determine… read more here.
Keywords: cell renal; ccrcc; dicer; mir 122 ... See more keywords
Etiologic heterogeneity of clear‐cell and papillary renal cell carcinoma in the Netherlands Cohort Study
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DOI: 10.1002/ijc.33193
Abstract: At present, mostly case‐control and retrospective studies have investigated the association between etiologic risk factors and the development of histologic subtypes of renal cell carcinoma (RCC). Therefore, we assessed the heterogeneity between body mass index… read more here.
Keywords: risk; ccrcc; heterogeneity; prcc risk ... See more keywords
Special issue “The advance of solid tumor research in China”: Multi‐omics analysis based on 1311 clear cell renal cell carcinoma samples identifies a glycolysis signature associated with prognosis and treatment response
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DOI: 10.1002/ijc.34121
Abstract: In clear cell renal cell carcinoma (ccRCC), glycolysis is enhanced mainly because of the increased expression of key enzymes in glycolysis. Hence, the discovery of new molecular biomarkers for glycolysis may help guide and establish… read more here.
Keywords: cell renal; cell; renal cell; ccrcc ... See more keywords
Genome‐wide screening and cohorts validation identifying novel lncRNAs as prognostic biomarkers for clear cell renal cell carcinoma
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.29478
Abstract: Clear cell renal cell carcinoma (ccRCC) is the main subtype of renal cell carcinoma with varied prognosis. We aimed to identify and assess the possible prognostic long noncoding RNA (lncRNA) biomarkers. LncRNAs expression data and… read more here.
Keywords: cell renal; renal cell; ccrcc; cell carcinoma ... See more keywords
G Protein γ subunit 7 loss contributes to progression of clear cell renal cell carcinoma
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.28597
Abstract: Clear cell renal cell carcinoma (ccRCC) is a common urinary neoplasm, looking for useful candidates to establish scientific foundation for the therapy of ccRCC is urgent. We downloaded genomic profiles of GSE781, GSE6244, GSE53757, and… read more here.
Keywords: cell renal; ccrcc; expression; gene ... See more keywords
Identification of methylation‐driven genes related to prognosis in clear‐cell renal cell carcinoma
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DOI: 10.1002/jcp.29046
Abstract: With the participation of the existing treatment methods, the prognosis of advanced clear‐cell renal cell carcinoma (ccRCC) is poor. More evidence indicates the presence of methylation in ccRCC cancer cells, but there is a lack… read more here.
Keywords: methylation; ccrcc; prognosis; methylation driven ... See more keywords
GBP2 serves as a novel prognostic biomarker and potential immune microenvironment indicator in renal cell carcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Carcinogenesis"
DOI: 10.1002/mc.23447
Abstract: Since the application of immune checkpoint therapy (ICT) has gradually become a new strategy for clear cell renal cell carcinoma (ccRCC) treatment, biomarkers that predict the individual response to ICT is needed. This study aimed… read more here.
Keywords: gbp2 expression; ccrcc; cell; indicator ... See more keywords
Juxtatumoral perinephric fat analysis in clear cell renal cell carcinoma
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DOI: 10.1007/s00261-018-1848-x
Abstract: PurposeThe purpose of the study was to evaluate the feasibility of using contrast-enhanced computed tomography (CECT)-based texture analysis (CTTA) metrics to differentiate between juxtatumoral perinephric fat (JPF) surrounding low-grade (ISUP 1–2) versus high-grade (ISUP 3–4)… read more here.
Keywords: ccrcc; grade; analysis; perinephric fat ... See more keywords
Predominantly cystic clear cell renal cell carcinoma and multilocular cystic renal neoplasm of low malignant potential form a low-grade spectrum
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DOI: 10.1007/s00428-018-2371-8
Abstract: Multilocular cystic renal cell carcinoma has been recently excluded from clear cell renal cell carcinoma (CCRCC) category and re-designated as multilocular cystic renal neoplasm of low malignant potential (MCRNLMP) due to its uniformly good outcomes.… read more here.
Keywords: ccrcc; cystic renal; cystic ccrcc; mcrnlmp ... See more keywords
TGFB1 mRNA expression is associated with poor prognosis and specific features of inflammation in ccRCC
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DOI: 10.1007/s00428-021-03256-6
Abstract: To determine whether TGFB1 affects the immune microenvironment of ccRCC, we investigated the association between TGFB1 expression and clinicopathological features. Tissue microarray was generated from 158 total or partial nephrectomy samples and 12 tumor-adjacent normal… read more here.
Keywords: expression; tgfb1 mrna; expression associated; ccrcc ... See more keywords
Comprehensive analysis of ceRNA networks to determine genes related to prognosis, overall survival, and immune infiltration in clear cell renal carcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Computers in biology and medicine"
DOI: 10.1016/j.compbiomed.2021.105043
Abstract: BACKGROUND Clear cell renal cell carcinoma (ccRCC) is one of the common subtypes of kidney cancer. Circular RNAs (circRNAs) act as competing endogenous RNAs (ceRNAs) to affect the expression of microRNAs (miRNAs), and hence the… read more here.
Keywords: analysis; expression; database; mir ... See more keywords