A phase I/II study of sitravatinib (MGCD-516) plus nivolumab in patients (pts) with metastatic clear-cell renal cell carcinoma (ccRCC) that progressed on prior VEGF-targeted therapy.
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DOI: 10.1200/jco.2018.36.6_suppl.tps708
Abstract: TPS708Background: Sitravatinib is a potent oral tyrosine kinase inhibitor that targets multiple receptor tyrosine kinase pathways including the vascular endothelial growth factor (VEGF), c-MET, and the Tyro3, Axl, and MER family. These pathways can allow… read more here.
Keywords: progressed prior; prior vegf; ccrcc progressed; therapy ... See more keywords