Abstract LB-304: Discovery of chemical probe CCT251236: An orally bioavailable efficacious pirin ligand from an HSF1 phenotypic screen
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DOI: 10.1158/1538-7445.am2017-lb-304
Abstract: Heat shock factor 1 (HSF1) was originally identified as a master regulator of the classical ‘cytoprotective’ heat shock response. However, a large body of evidence has now verified the importance of HSF1 to tumorigenesis and… read more here.
Keywords: phenotypic screen; probe; hsf1; pirin ... See more keywords