Chaperonin containing TCP1 subunit 3 (CCT3) promotes cisplatin resistance of lung adenocarcinoma cells through targeting the Janus kinase 2/signal transducers and activators of transcription 3 (JAK2/STAT3) pathway.
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DOI: 10.1080/21655979.2021.1971030
Abstract: Cisplatin resistance remains a major obstacle to effective chemotherapies for non-small cell lung cancer (NSCLC). Chaperonin containing TCP1 subunit 3 (CCT3) has been extensively investigated in various cancers, but not in the context of drug… read more here.
Keywords: jak2 stat3; cct3; a549 ddp; resistance ... See more keywords
Insights into the roles and driving forces of CCT3 in human tumors
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DOI: 10.3389/fphar.2022.1005855
Abstract: CCT3 played a key role in many cancers. This study aimed to further explore the characteristics of CCT3 from a pan-cancer perspective and reveal the driving forces for CCT3. By bioinformatic analysis, we found that… read more here.
Keywords: cct3; forces cct3; cct3 expression; expression ... See more keywords
Suppression of CCT3 inhibits malignant proliferation of human papillary thyroid carcinoma cell
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DOI: 10.3892/ol.2018.8496
Abstract: Papillary thyroid carcinoma (PTC) is the most frequently occurring subtype of thyroid cancer. A certain portion of PTCs can progress to recurrent metastatic cancer. Currently, there remains no effective molecular target therapy for PTCs. As… read more here.
Keywords: carcinoma; proliferation; cct3; ptc ... See more keywords