NRBF2 is a RAB7 effector required for autophagosome maturation and mediates the association of APP-CTFs with active form of RAB7 for degradation
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DOI: 10.1080/15548627.2020.1760623
Abstract: ABSTRACT NRBF2 is a component of the class III phosphatidylinositol 3-kinase (PtdIns3K) complex. Our previous study has revealed its role in regulating ATG14-associated PtdIns3K activity for autophagosome initiation. In this study, we revealed an unknown… read more here.
Keywords: protein; autophagosome maturation; degradation; ccz1 ... See more keywords