CD137 Signaling Regulates Acute Colitis via RALDH2-Expressing CD11b-CD103+ DCs.
Sign Up to like & getrecommendations! Published in 2020 at "Cell reports"
DOI: 10.1016/j.celrep.2020.02.103
Abstract: CD137, a potent costimulatory receptor for CD8+ T cells, is expressed in various non-T cells, but little is known about its regulatory functions in these cells. In this study, we show that CD137 signaling, specifically in… read more here.
Keywords: cd103 dcs; cd11b cd103; cd103; cd137 signaling ... See more keywords
Abstract B05: Adenosine generation limits the ability of radiation therapy to induce antitumor immunity by abrogating recruitment and activation of CD103+ DCs
Sign Up to like & getrecommendations! Published in 2018 at "Cancer immunology research"
DOI: 10.1158/2326-6074.tumimm17-b05
Abstract: Localized radiation therapy (RT) can act as a powerful adjuvant to immunotherapeutic strategies by triggering anti-tumor immune responses to poorly immunogenic tumors. Radiation of tumor cells induces a dose-dependent release of ATP, a molecule that… read more here.
Keywords: cd103 dcs; adenosine generation; dcs; activation ... See more keywords
Microbiota-activated CD103+ DCs stemming from microbiota adaptation specifically drive γδT17 proliferation and activation
Sign Up to like & getrecommendations! Published in 2017 at "Microbiome"
DOI: 10.1186/s40168-017-0263-9
Abstract: BackgroundIL-17-producing γδT cells (γδT17) promote autoinflammatory diseases and cancers. Yet, γδT17 peripheral regulation has not been thoroughly explored especially in the context of microbiota-host interaction. The potent antigen-presenting CD103+ dendritic cell (DC) is a key… read more here.
Keywords: cd103 dcs; microbiota; t17; activated cd103 ... See more keywords