Modulation of CD11c+ lung dendritic cells in respect to TGF‐β in experimental pulmonary fibrosis
Sign Up to like & getrecommendations! Published in 2017 at "Cell Biology International"
DOI: 10.1002/cbin.10800
Abstract: Idiopathic pulmonary fibrosis (IPF) is a deadly, progressive lung disease with very few treatment options till now. Bleomycin‐induced pulmonary fibrosis (BIPF) is a commonly used mice model in IPF research. TGF‐β1 has been shown to… read more here.
Keywords: cd11c; dcs; tgf; pulmonary fibrosis ... See more keywords
CD11c identifies microbiota and EGR2‐dependent MHCII+ serous cavity macrophages with sexually dimorphic fate in mice
Sign Up to like & getrecommendations! Published in 2022 at "European Journal of Immunology"
DOI: 10.1002/eji.202149756
Abstract: The murine serous cavities contain a rare and enigmatic population of short‐lived F4/80loMHCII+ macrophages but what regulates their development, survival, and fate is unclear. Here, we show that mature F4/80loMHCII+ peritoneal macrophages arise after birth,… read more here.
Keywords: cavity; cd11c; cavity macrophages; serous cavity ... See more keywords
Modulation of surface CD11c expression tracks plasticity in murine intestinal tissue eosinophils
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Leukocyte Biology"
DOI: 10.1002/jlb.3hi0821-432rr
Abstract: Intestinal eosinophils are implicated in the inflammatory pathology of eosinophilic gastrointestinal diseases and inflammatory bowel diseases. Eosinophils also contribute to intestinal immunologic and tissue homeostasis and host defense. Recent studies in allergic airway disease suggest… read more here.
Keywords: cd11c; intestinal eosinophils; surface cd11c; cd11c expression ... See more keywords
Distinct Kinase-Independent Role of RIPK3 in CD11c+ Mononuclear Phagocytes in Cytokine-Induced Tissue Repair.
Sign Up to like & getrecommendations! Published in 2017 at "Cell reports"
DOI: 10.1016/j.celrep.2017.02.015
Abstract: Receptor interacting protein kinase 3 (RIPK3) induces necroptosis, a type of regulated necrosis, through its kinase domain and receptor interacting protein (RIP) homotypic interaction motif (RHIM). In addition, RIPK3 has been shown to regulate NLRP3 inflammasome… read more here.
Keywords: mononuclear phagocytes; cd11c; kinase; ripk3 ... See more keywords
Distinctly regulated functions and mobilization of CD11c-positive cells elicited by TLR3- and IPS-1 signaling in the cornea.
Sign Up to like & getrecommendations! Published in 2019 at "Immunology letters"
DOI: 10.1016/j.imlet.2018.12.004
Abstract: The human ocular surface epithelium expresses TLR3, which recognizes double-stranded (ds) RNA mimicking polyinosine-polycytidylic acid (polyI:C). Its stimulation induces the secretion of the inflammatory cytokines such as interleukin (IL)-6, IL-8, and type I interferon. The… read more here.
Keywords: cornea; cd11c; yfp mice; cd11c yfp ... See more keywords
Depletion of CD11c+ dendritic cells in apolipoprotein E-deficient mice limits angiotensin II-induced abdominal aortic aneurysm formation and growth.
Sign Up to like & getrecommendations! Published in 2019 at "Clinical science"
DOI: 10.1042/cs20190924
Abstract: OBJECTIVE The role of chronic inflammation in abdominal aortic aneurysm (AAA) is controversial. CD11c+ antigen-presenting cells (APCs) (dendritic cells (DCs)) have been reported in human AAA samples but their role is unclear. The effect of… read more here.
Keywords: cd11c; depletion cd11c; aortic aneurysm; depletion ... See more keywords
Definition of a mouse microglial subset that regulates neuronal development and proinflammatory responses in the brain
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2116241119
Abstract: Significance CD11c+ microglia enriched for osteopontin (OPN) expression appear at distinct stages of brain development, aging, and several neurodegenerative disorders. Whether coexpression of CD11c and OPN results from microglial activation or represents a part of… read more here.
Keywords: cd11c; definition; microglial subset; development ... See more keywords
Adhesive Interactions between Mononuclear Phagocytes and Intestinal Epithelium Perturb Normal Epithelial Differentiation and Serve as a Therapeutic Target in Inflammatory Bowel Disease
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Crohn's and Colitis"
DOI: 10.1093/ecco-jcc/jjy088
Abstract: Background and Aims Disturbance of intestinal homeostasis is associated with the development of inflammatory bowel disease [IBD], and TGF-β signalling impairment in mononuclear phagocytes [MPs] causes murine colitis with goblet cell depletion. Here, we examined… read more here.
Keywords: colitis; cd11c; cd11c cre; cre tgfbr2fl ... See more keywords
Lactobacillus brevis KB290 With Vitamin A Ameliorates Murine Intestinal Inflammation Associated With the Increase of CD11c+ Macrophage/CD103- Dendritic Cell Ratio.
Sign Up to like & getrecommendations! Published in 2018 at "Inflammatory bowel diseases"
DOI: 10.1093/ibd/izx003
Abstract: Background The ratio of colonic anti-inflammatory CD11c+ macrophages (MPs) to inflammatory CD103- dendritic cells (DCs) plays pivotal roles in intestinal inflammation. Little is known about how the ratio is regulated by lactic acid bacteria (LAB)… read more here.
Keywords: cd11c; intestinal inflammation; cd103; ratio ... See more keywords
Targeting of SIRPα as a potential therapy for Langerhans cell histiocytosis
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Science"
DOI: 10.1111/cas.15758
Abstract: Langerhans cell histiocytosis (LCH) is a rare neoplastic disorder characterized by inflammatory lesions arising from the anomalous accumulation of pathogenic CD1a+CD207+ dendritic cells (DCs). SIRPα is a transmembrane protein highly expressed in myeloid cells such… read more here.
Keywords: cd11c; langerhans cell; lch; cell histiocytosis ... See more keywords
Conditional knockout of oestrogen receptor alpha in CD11c+ cells impacts female survival and inflammatory cytokine profile in murine lupus
Sign Up to like & getrecommendations! Published in 2022 at "Immunology"
DOI: 10.1111/imm.13541
Abstract: Oestrogen and oestrogen receptor alpha (ERα) have been implicated in systemic lupus erythematosus pathogenesis. ERα signalling influences dendritic cell (DC) development and function, as well as inflammation and downstream immune responses. We previously reported that… read more here.
Keywords: cd11c; cd11c cells; oestrogen receptor; mice ... See more keywords