Impact of CD123 expression, analyzed by immunohistochemistry, on clinical outcomes in patients with acute myeloid leukemia
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DOI: 10.1007/s12185-019-02616-y
Abstract: Aberrant expression of the interleukin-3 receptor alpha chain (IL3RA or CD123) is frequently observed in patients with a subset of leukemic disorders, including acute myeloid leukemia (AML), particularly in leukemia stem cells. We analyzed the… read more here.
Keywords: clinical outcomes; myeloid leukemia; novo aml; expression ... See more keywords
Prognostic value of CD25/CD123 pattern of expression in acute myeloid leukemia patients with normal cytogenetic
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DOI: 10.1016/j.lrr.2020.100203
Abstract: This study was designed to assess the significance of interleukin-2 receptor (CD25) and inteleukin-3 receptor (CD123) expression in cytogenetically normal acute myeloid leukemia (CN-AML) patients. The current study includes 80 CN-AML (≤ 60 years) before… read more here.
Keywords: cd123 expression; cd25 cd123; expression; acute myeloid ... See more keywords
FLT3‐ITD DNA and mRNA levels in AML do not correlate with CD7, CD33 and CD123 expression
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DOI: 10.1111/jcmm.15255
Abstract: FLT3 internal tandem duplication (ITD) mutations are found in around 25% of all acute myeloid leukaemia (AML) cases and is associated with shorter disease‐free and overall survival. Previous reports have shown that FLT3‐ITD induces a… read more here.
Keywords: flt3 itd; itd; cd123 expression; cd33 cd123 ... See more keywords